The developmental dynamics of the human male germline
J Hargy, K Sasaki - Development, 2023 - journals.biologists.com
… Male germ cell development starts when pluripotent cells undergo … to the first wave of
spermatogenesis that generates functional … through apoptotic cell death. Notably, some M-pro-…
spermatogenesis that generates functional … through apoptotic cell death. Notably, some M-pro-…
The foundational framework of tumors: Gametogenesis, p53, and cancer
… are often removed through programmed cell death in a p53-… restricted to immature germ cells,
such as spermatogonia and oogonia/… The function of most CT antigens is unclear since the …
such as spermatogonia and oogonia/… The function of most CT antigens is unclear since the …
[HTML][HTML] Hormone Regulation in Testicular Development and Function
L Li, W Lin, Z Wang, R Huang, H Xia, Z Li… - International Journal of …, 2024 - mdpi.com
… In the early stage of meiosis, FSH protects spermatocytes from … increased germ cell apoptosis
and disruptions in spermatogenesis [141]. The involvement of estrogen in the development …
and disruptions in spermatogenesis [141]. The involvement of estrogen in the development …
[HTML][HTML] Molecular regulation of copper homeostasis in the male gonad during the process of spermatogenesis
S Herman, P Lipiński, M Ogórek, R Starzyński… - International journal of …, 2020 - mdpi.com
… that primary spermatocytes died through apoptosis [64]. In the … in primary spermatocytes is
of key importance for germ cells at … suggest that the function of ATP7B in myoid cells might be …
of key importance for germ cells at … suggest that the function of ATP7B in myoid cells might be …
[HTML][HTML] Chemotherapy induced damage to spermatogonial stem cells in prepubertal mouse in vitro impairs long-term spermatogenesis
F Lopes, P Tholeti, SK Adiga, RA Anderson… - Toxicology Reports, 2021 - Elsevier
… ex vivo spermatogenesis in prepubertal mouse testis, as first … inducing apoptosis in germ
cells, as they do in neoplastic cells [… of spermatogenesis, we evaluated key stages of germ cell …
cells, as they do in neoplastic cells [… of spermatogenesis, we evaluated key stages of germ cell …
Regulation of spermatogonial stem cell self-renewal and proliferation in mammals
BH Wei, SL Hao, WX Yang - 2022 - digitum.um.es
… of male germ cells depends on spermatogenesis, which can … Loss function of OCT4 in mouse
showed the embryonic lethal… in the primordial germ cells led to germline cell death (Nichols …
showed the embryonic lethal… in the primordial germ cells led to germline cell death (Nichols …
The Death of Sperm Cells
KK Kavaldzhieva, DK Dimitrova-Dikanarova… - Acta Medica …, 2023 - sciendo.com
… The first prerequisite for sperm cells to be functional is, of course… the current state of
knowledge about male germ cell death. … During the first spermatogenic wave, apoptosis of large …
knowledge about male germ cell death. … During the first spermatogenic wave, apoptosis of large …
[HTML][HTML] The molecular mechanism of sex hormones on Sertoli cell development and proliferation
… cells may facilitate the timely onset of the first spermatogenic … necessary to investigate its
actual function in postnatal testis … of spermatogenesis and increased germ cell apoptosis (108). …
actual function in postnatal testis … of spermatogenesis and increased germ cell apoptosis (108). …
[HTML][HTML] TRIM71 Deficiency Causes Germ Cell Loss During Mouse Embryogenesis and Is Associated With Human Male Infertility
LA Torres-Fernández, J Emich, Y Port… - … and Developmental …, 2021 - frontiersin.org
… TRIM71 function is essential for embryogenesis and its … spermatogonia, also known as
spermatogonial stem cells (SSCs… nor signs of abnormal cell death upon regular media change, …
spermatogonial stem cells (SSCs… nor signs of abnormal cell death upon regular media change, …
COP9 signalosome complex subunit 5, an IFT20 binding partner, is essential to maintain male germ cell survival and acrosome biogenesis
Q Huang, H Liu, J Zeng, W Li, S Zhang… - Biology of …, 2020 - academic.oup.com
… was present in cytoplasm of spermatocytes, the acrosome of … investigate its function in
male germ cells, we used germ cell-… in male germ cells, regulation of spermatocyte apoptosis, …
male germ cells, we used germ cell-… in male germ cells, regulation of spermatocyte apoptosis, …