Functional primordial germ cell–like cells from pluripotent stem cells in rats
M Oikawa, H Kobayashi, M Sanbo, N Mizuno… - Science, 2022 - science.org
… However, low numbers (~40 in mice) of PGCs in early … aggregate-like embryoid bodies without
extensive cell death (fig. S1D). … the male rPGCLCs undergo spermatogenesis in vivo after …
extensive cell death (fig. S1D). … the male rPGCLCs undergo spermatogenesis in vivo after …
Conditional deletion of Hspa5 leads to spermatogenesis failure and male infertility in mice
Z Wen, H Zhu, J Wang, B Wu, A Zhang, H Zhao… - Life Sciences, 2023 - Elsevier
… the function of HSPA5 in spermatogenesis and male reproduction, we established germ cell-…
Also, Hspa4 deficiency induces spermatogenic cell apoptosis and reduces the total number …
Also, Hspa4 deficiency induces spermatogenic cell apoptosis and reduces the total number …
[PDF][PDF] Single-cell RNA sequencing of human, macaque, and mouse testes uncovers conserved and divergent features of mammalian spermatogenesis
… in somatic cell type relatedness or plasticity, functional roles, … for future studies of germ cell
development and inform fertility … states and/or the balance of cell division and death. Humans …
development and inform fertility … states and/or the balance of cell division and death. Humans …
A subpopulation of human Adark spermatogonia behaves as the reserve stem cell
AL Caldeira-Brant, LM Martinelli, MM Marques… - …, 2020 - rep.bioscientifica.com
… number of mitotic and apoptotic spermatogonia per 100 SCN. It … we used the six-stage germ
cell association (Clermont 1963)… molecular/functional evaluations are required to understand …
cell association (Clermont 1963)… molecular/functional evaluations are required to understand …
[HTML][HTML] Comparative transcriptional analysis uncovers molecular processes in early and mature somatic cyst cells of Drosophila testes
VE Adashev, SS Bazylev, DM Potashnikova… - … Journal of Cell Biology, 2022 - Elsevier
… , thus forming a functional unit of spermatogenesis – the cyst. … and germ cells at different
stages of spermatogenesis have been … cyst cells at the different stages of spermatogenesis from …
stages of spermatogenesis have been … cyst cells at the different stages of spermatogenesis from …
Testicular macrophages: development and function in health and disease
A Meinhardt, N Dejucq-Rainsford, S Bhushan - Trends in Immunology, 2022 - cell.com
… cells, which are in intimate contact with the developing germ … barrier, steroidogenesis, and
spermatogenesis. Testicular … The first wave generates macrophage progenitors from early …
spermatogenesis. Testicular … The first wave generates macrophage progenitors from early …
STRA8 induces transcriptional changes in germ cells during spermatogonial development
RL Gewiss, EA Shelden… - … and development, 2021 - Wiley Online Library
… development but its function in spermatogonia has not been … changes in the first round
of germ cells to undergo … across the first wave of spermatogonial development in both …
of germ cells to undergo … across the first wave of spermatogonial development in both …
[HTML][HTML] Immune cell subtypes and their function in the testis
S Bhushan, MS Theas, VA Guazzone… - Frontiers in …, 2020 - frontiersin.org
… spermatogenesis, germ cells divide and mature in close association with somatic Sertoli cells
(… in the testis quickly resolves after the initial infiltration of immune cells and impairment of …
(… in the testis quickly resolves after the initial infiltration of immune cells and impairment of …
Critical and different roles of DNA methylation in male germ cell development
M Dura - 2021 - theses.fr
… However, the precise targets and developmental function of … germ cell fates during the first
wave of spermatogenesis. Fetal … spermatogonia (cKIT-positive) that enter the first “round” of …
wave of spermatogenesis. Fetal … spermatogonia (cKIT-positive) that enter the first “round” of …
Involvement of GLCCI1 in mouse spermatogenesis
M Takada, D Fukuhara, T Takiura… - The FASEB …, 2023 - Wiley Online Library
… germ cell during spermatogenesis requires a functional … contributes to development and
maintenance during spermatogenesis.… the massive wave of germ cell apoptosis during the first …
maintenance during spermatogenesis.… the massive wave of germ cell apoptosis during the first …