[HTML][HTML] Several routes of cell death to secondary necrosis in the elasmobranch testis

LM McClusky - Apoptosis, 2022 - Springer
spermatogenesis features significant germ cell loss through … G2-cyst showing the initial
stages of cell death reveals only a … of spermatogenesis [30] and are therefore functionally still …

[HTML][HTML] Effect of low energy shock wave on testicular microenvironment homeostasis in rats

J Xing, G Yu, Y Xiang, H Xu, Z Liu, Z Bai - Ecotoxicology and Environmental …, 2022 - Elsevier
… , which can cause a certain degree of damage to rat testicular function. It has been shown
that germ cell apoptosis has particular effects on spermatogenic epithelium function (Cheng et …

[PDF][PDF] A multistate stem cell dynamics maintains homeostasis in mouse spermatogenesis

T Nakagawa, DJ Jörg, H Watanabe, S Mizuno, S Han… - Cell Reports, 2021 - cell.com
Spermatogenic stem cell (SSC) function resides within … , comprising <1% of testicular germ
cells. Aundiff produces differentiating … First, we found that labeled X cells did not perfectly self-…

[HTML][HTML] The role of tyrosine phosphatase Shp2 in spermatogonial differentiation and spermatocyte meiosis

Y Li, WS Liu, J Yi, SB Kong, JC Ding… - Asian journal of …, 2020 - journals.lww.com
… transition from spermatogonia to spermatocytes, we deleted Shp2 in postnatal germ cells in
… meiosis in Shp2-deficient spermatocytes leads to cell death. Furthermore, we found that the …

[HTML][HTML] Consequences of Exposure to Hypobaric Hypoxia Associated with High Altitude on Spermatogenesis and Seminal Parameters: A Literature Review

C Cornejo-Guerra, C Salazar-Ardiles, P Morales… - Cells, 2024 - mdpi.com
… The first observations of impaired human spermatogenesis … , negatively impacting cellular
function and altering the … the apoptosis rate of germ cells, particularly spermatogonia and …

[PDF][PDF] Autoimmune regulator enhanced the expression of caspase-3 and did not induce massive germ cell apoptosis in GC1-Spg cells

KP Bhagya, RJ Aswathy… - Cell Physiol …, 2020 - cellphysiolbiochem.com
… that C18-4 cells which are derived from Type A spermatogonia … of apoptotic cells in testis at
an early phase of germ cell … GC-1spg cells overexpressing Aire and three functional domains …

[HTML][HTML] Throughout in vitro first spermatogenic wave: Next-generation sequencing gene expression patterns of fresh and cryopreserved prepubertal mice testicular …

L Dumont, H Lopez Maestre, F Chalmel… - Frontiers in …, 2023 - frontiersin.org
first wave of in vitro spermatogenesis. Since proper development of male germ cells requires
correct function … (2.7-fold) when germ cell apoptosis is induced by intratesticular hormonal …

[HTML][HTML] Loss of ubiquitin carboxy-terminal hydrolase L1 impairs long-term differentiation competence and metabolic regulation in murine spermatogonial stem cells

WF Alpaugh, AL Voigt, R Dardari, L Su, I Al Khatib… - Cells, 2021 - mdpi.com
… tubules were spermatogonia and Sertoli cells, we … early and massive wave of germ cell
apoptosis during the pre-pubertal stage of development, a phase that is essential for functional

[HTML][HTML] Proteostasis in the male and female germline: a new outlook on the maintenance of reproductive health

SL Cafe, B Nixon, H Ecroyd, JH Martin… - … and developmental …, 2021 - frontiersin.org
… Male germ cells are produced through successive waves of spermatogenesis occurring …
-zona pellucida binding, increased sperm cell death and agglutination. Furthermore, incubation …

[HTML][HTML] Fetal Origin Programming of the Male Reproductive System

Y Fujisawa, O Tsutomu - … Advances in Male Reproductive System, 2023 - intechopen.com
… In mice, a key event in the early stages of testis differentiation is … of-function in germ cells
causes spermatogenic failure in mice [33] and activation of Esr2 causes spermatocyte apoptosis