… mortality with andexanetáalfa vs 4-factor prothrombin complex concentrate for factor Xa inhibitor-related major bleeding in a US hospital-based observational study

PP Dobesh, GJ Fermann, MJ Christoph, B Koch… - Research and Practice …, 2023 - Elsevier
… ), a record of use of the factor Xa inhibitors rivaroxaban or apixaban, andexanetáalfa or 4F-PCC
… with other bleed types, lack of reporting on the time since the last dose of FXa inhibitor or …

An 18-month single-center observational study of real-world use of andexanet alfa in patients with factor Xa inhibitor associated intracranial hemorrhage

A Giovino, E Shomo, KV Busey, D Case… - Clinical Neurology and …, 2020 - Elsevier
… bleeding associated with the use of rivaroxaban or apixaban. Controversy exists over the …
To our knowledge, this is the largest reported single center observational study of real-world …

Efficacy and safety of rivaroxaban versus apixaban for venous thromboembolism: A systematic review and meta-analysis of observational studies

D Fredman, R McNeil, O Eldar, A Leader… - Journal of Thrombosis …, 2024 - Springer
studies that directly compared treatment with rivaroxaban and apixaban in adult patients with
acute VTE and reported both … published study comparing PK properties and anti-factor Xa

[HTML][HTML] Comparative effectiveness and safety of edoxaban, rivaroxaban, and apixaban in patients with venous thromboembolism: A cohort study

T Fukasawa, T Seki, M Nakashima… - Journal of Thrombosis and …, 2022 - Elsevier
factor Xa inhibitors (edoxaban, rivaroxaban, and apixaban) … Although several observational
studies have compared the … We used ICD‐10 codes recorded in either DPC claims or FFS …

Effectiveness and safety of apixaban compared with rivaroxaban for patients with atrial fibrillation in routine practice: a cohort study

M Fralick, M Colacci, S Schneeweiss… - Annals of internal …, 2020 - acpjournals.org
… also reported a decreased risk for major bleeding with apixaban… Our observational study had
several limitations. First, we … peak antifactor Xa levels in patients receiving apixaban might …

… and safety between apixaban, dabigatran, edoxaban, and rivaroxaban among patients with atrial fibrillation: a multinational population-based cohort study

WCY Lau, CO Torre, KKC Man, HM Stewart… - Annals of Internal …, 2022 - acpjournals.org
… previously reported in the Korean population (36). … In addition, as with all observational
studies, we cannot rule out the … antidote to oral factor Xa inhibitors (rivaroxaban, apixaban, and …

Apixaban and rivaroxaban anti-Xa level utilization and associated bleeding events within an academic health system

N Jakowenko, S Nguyen, M Ruegger, A Dinh… - Thrombosis research, 2020 - Elsevier
… This retrospective, observational cohort study was approved by … All anti-Xa levels for
apixaban and rivaroxaban ordered at … Lastly, the reported upper limit of our institution's anti-Xa

Apixaban use in obese patients: a review of the pharmacokinetic, interventional, and observational study data

MJ Jamieson, W Byon, RW Dettloff, M Crawford… - American Journal of …, 2022 - Springer
… that standard doses of apixaban or rivaroxaban, along with … apixaban exposure. Although
the chromogenic assay used to support apixaban clinical development reported anti-factor Xa

Final study report of andexanet alfa for major bleeding with factor Xa inhibitors

TJ Milling Jr, S Middeldorp, L Xu, B Koch, A Demchuk… - Circulation, 2023 - Am Heart Assoc
… In May 2018, the US Food and Drug Administration approved andexanet alfa for the
reversal of anticoagulation with apixaban and rivaroxaban in life-threatening or uncontrolled …

Clinical Characteristics and Incidence of Hemorrhagic Complications in Patients Taking Factor Xa Inhibitors in Spain: A Long-Term Observational Study

C Escobar, B Palacios, M Villarreal, M Gutiérrez… - Journal of Clinical …, 2024 - mdpi.com
apixaban, edoxaban, or rivaroxaban) or enoxaparin (only in active cancer patients) constituted
the start of the observational … pg inhibitors, which may interact with DOACs, were recorded