A review of scientific evidence for THC: CBD oromucosal spray (nabiximols) in the management of chronic pain

MA Überall - Journal of pain research, 2020 - Taylor & Francis
… A subsequent open-label extension study involving 39 patients … , with some patients
maintaining long-term (up to 2 years) … studies in patients with chronic cancer-related or …

Safety and tolerability of nabiximols oromucosal spray: a review of more than 15 years” accumulated evidence from clinical trials

JM Prieto Gonzalez, C Vila Silvan - Expert Review of …, 2021 - Taylor & Francis
… reports safety data from RCTs and related open-label studies … were considered to be
cancer-related and not related to … capsules, dronabinol, nabilone and THC/CBD oral capsules …

[HTML][HTML] Effects of cannabinoids on pain control, quality of life and opioid-sparing in cancer patients: systematic review

SS Sá, C Melo-Alvim, P Reis-Pina - BrJP, 2023 - SciELO Brasil
… An open-label extension study to investigate the long-term safety and tolerability of THC/CBD
oromucosal spray and … cancer-related pain refractory to strong opioid analgesics. J …

[HTML][HTML] Clinical research evidence supporting administration and dosing recommendations of medicinal cannabis as analgesic in cancer patients

C Christensen, M Allesø, M Rose, C Cornett - Journal of Clinical …, 2022 - mdpi.com
cannabis to patients suffering from cancer-related pains. Only clinical … open-label extension
study to investigate the long-term safety and tolerability of THC/CBD oromucosal spray

… , safety, and tolerability of nabiximols oromucosal spray vs typical oral long-acting opioid analgesics in patients with severe neuropathic back pain: Analysis of 6-month …

MA Ueberall, C Vila Silván, U Essner… - Pain …, 2022 - academic.oup.com
… or second-line therapy or for long-term treatment [1]. Nevertheless, … This was a retrospective,
open-label, parallel-group, flexible-… of patients with active cancer and/or cancer-related pain; …

… trial of medical cannabis in patients with stage IV cancers to assess feasibility, dose requirements, impact on pain and opioid use, safety, and overall patient …

DM Zylla, J Eklund, G Gilmore, A Gavenda… - Supportive Care in …, 2021 - Springer
… goals and tolerance. Dispensaries provided records of all … with a specific THC/CBD dose.
The mean, median, and range at … in non-cancer-related pain [16], we analyzed pain and total …

[HTML][HTML] A scoping review on clinical trials of pain reduction with cannabis administration in adults

R Haleem, R Wright - Journal of clinical medicine research, 2020 - ncbi.nlm.nih.gov
… is a cannabis extract containing fixed doses of THC-CBD, THC or … , oral spray) in 43 patients
with cancer-related pain and … Most non-randomized trials were single-arm, open-label with …

[HTML][HTML] Practical Considerations for the Use of Cannabis in Cancer Pain Management—What a Medical Oncologist Should Know

A Gorzo, A Havași, Ș Spînu, A Oprea, C Burz… - Journal of Clinical …, 2022 - mdpi.com
… Up to 40% of the patients with cancer-related pain have neuropathic … A long-term observational
study conducted in Israel … (producing effective pain management with tolerable adverse …

Opioid analgesics for nociceptive cancer pain: A comprehensive review

C Abdel Shaheed, C Hayes, CG Maher… - CA: A Cancer …, 2024 - Wiley Online Library
pain), whereas one was an openlabel trial in 174 people that … [THC], cannabidiol [CBD],
THC:CBD combinations, THC … with cancerrelated pain,272 and opioid‐related deaths in …

[HTML][HTML] Role of cannabidiol for improvement of the quality of life in cancer patients: potential and challenges

R Green, R Khalil, SS Mohapatra… - International Journal of …, 2022 - mdpi.com
… its effectiveness to alleviate cancer-related pain [79]. This study was open-label with a self-…
In patients with pain due to spinal cord injury, oral THC/CBD self-administered up to 130 mg/…