Monoclonal antibodies in cancer therapy
D Zahavi, L Weiner - Antibodies, 2020 - mdpi.com
… To better understand how monoclonal antibodies function as a cancer therapy, we review
their structure, mechanisms of action, clinical uses, mechanisms of resistance, and some …
their structure, mechanisms of action, clinical uses, mechanisms of resistance, and some …
Mechanisms of therapeutic antitumor monoclonal antibodies
… In this review, we summarize the different therapeutic mAbs that … our current understanding
of their different mechanisms of antitumor … activation are being developed for clinical use (17). …
of their different mechanisms of antitumor … activation are being developed for clinical use (17). …
Development of therapeutic antibodies for the treatment of diseases
… The global therapeutic monoclonal antibody market was valued … This review summarizes the
latest market trends and outlines … research and potential for their clinical use. Other scientific …
latest market trends and outlines … research and potential for their clinical use. Other scientific …
[HTML][HTML] Monoclonal antibody-based molecular imaging strategies and theranostic opportunities
N Dammes, D Peer - Theranostics, 2020 - ncbi.nlm.nih.gov
… review covered the application of monoclonal antibodies in a variety of molecular imaging
modalities. Three major applications … in patients will drive the transition to clinical applications. …
modalities. Three major applications … in patients will drive the transition to clinical applications. …
An update to monoclonal antibody as therapeutic option against COVID-19
P Deb, MMA Molla, KM Saif-Ur-Rahman - Biosafety and Health, 2021 - mednexus.org
… This brief review discusses the mechanism of action and updates to clinical trials of different
monoclonal antibodies used to treat COVID-19, with … trials were included within this review. …
monoclonal antibodies used to treat COVID-19, with … trials were included within this review. …
Bispecific antibodies: from research to clinical application
J Ma, Y Mo, M Tang, J Shen, Y Qi, W Zhao… - Frontiers in …, 2021 - frontiersin.org
… those of monoclonal antibodies (MoAbs), with broad applications for … review provides a
comprehensive and systematic summary of the classic platforms, mechanisms, and applications …
comprehensive and systematic summary of the classic platforms, mechanisms, and applications …
[HTML][HTML] Phage display derived monoclonal antibodies: from bench to bedside
MA Alfaleh, HO Alsaab, AB Mahmoud… - Frontiers in …, 2020 - frontiersin.org
… This review will illustrate the utility of phage display as a powerful platform for therapeutic
antibodies … To date, more than 80 mAbs have been approved for clinical applications with many …
antibodies … To date, more than 80 mAbs have been approved for clinical applications with many …
Clinical development of immunotherapies for HER2+ breast cancer: a review of HER2-directed monoclonal antibodies and beyond
RLB Costa, BJ Czerniecki - NPJ Breast Cancer, 2020 - nature.com
… Nonetheless, the standardization of measures of immune activation and biomarkers
predictive of benefit from therapy are lacking for both preclinical and clinical use. In addition, …
predictive of benefit from therapy are lacking for both preclinical and clinical use. In addition, …
Emerging new therapeutic antibody derivatives for cancer treatment
S Jin, Y Sun, X Liang, X Gu, J Ning, Y Xu… - … and Targeted Therapy, 2022 - nature.com
… In this review, we summarize antibodies of various molecular types, … Therapeutic application
of monoclonal antibodies (mAbs) emerged after the hybridoma technique to produce mAbs …
of monoclonal antibodies (mAbs) emerged after the hybridoma technique to produce mAbs …
[HTML][HTML] Recent advances of antibody drug conjugates for clinical applications
P Zhao, Y Zhang, W Li, C Jeanty, G Xiang… - … Pharmaceutica Sinica B, 2020 - Elsevier
… In this review, we provide an overview of ADCs in preclinical and … therapeutic window limit
their clinical use 3 . The advances of monoclonal antibody provide opportunities to use their …
their clinical use 3 . The advances of monoclonal antibody provide opportunities to use their …