[HTML][HTML] Antibodies to combat viral infections: development strategies and progress
G Pantaleo, B Correia, C Fenwick, VS Joo… - Nature Reviews Drug …, 2022 - nature.com
… the generation of monoclonal antibodies (mAbs) by Köhler and … In this Review, we first
provide an overview of the … Most therapeutic mAbs in clinical use or development against …
provide an overview of the … Most therapeutic mAbs in clinical use or development against …
[HTML][HTML] Impact of anti-amyloid-β monoclonal antibodies on the pathology and clinical profile of Alzheimer's disease: a focus on aducanumab and lecanemab
M Shi, F Chu, F Zhu, J Zhu - Frontiers in aging neuroscience, 2022 - frontiersin.org
… review, we summarized recent studies on the therapeutic effects and clinical trial results of
these mabs … impact of aducanumab and lecanemab on AD pathology and clinical profiles. The …
these mabs … impact of aducanumab and lecanemab on AD pathology and clinical profiles. The …
[HTML][HTML] Tackling COVID-19 with neutralizing monoclonal antibodies
… therapeutics for other infectious diseases. Here, we provide an overview of SARS-CoV-2-neutralizing
mAbs, including their … the clinical trials of approved or late-stage mAb therapeutics. …
mAbs, including their … the clinical trials of approved or late-stage mAb therapeutics. …
[HTML][HTML] Hybridoma technology; advancements, clinical significance, and future aspects
S Mitra, PC Tomar - Journal of Genetic Engineering and Biotechnology, 2021 - Springer
… This review discusses the advantages and challenges associated with monoclonal
antibody … rights to a wide range of monoclonal antibodies for therapeutic application. These …
antibody … rights to a wide range of monoclonal antibodies for therapeutic application. These …
[HTML][HTML] An overview of antibody conjugated polymeric nanoparticles for breast cancer therapy
… Drug delivery systems (DDS) can be optimized for clinical applications by controlling these
… monoclonal antibody for generating novel nanomedicines for breast cancer therapy by far. …
… monoclonal antibody for generating novel nanomedicines for breast cancer therapy by far. …
Antibody–drug conjugates: a comprehensive review
… the antibody is linked to the payload are key determinants of the safety and efficacy of ADCs.
This review provides an overview … At present, four ADCs are in clinical use approved by the …
This review provides an overview … At present, four ADCs are in clinical use approved by the …
Challenges and strategies for next-generation bispecific antibody-based antitumor therapeutics
H Li, P Er Saw, E Song - Cellular & molecular immunology, 2020 - nature.com
… In this review, we mainly discuss previous and current … in technical development and their
clinical applications. … BsAb bispecific antibody, Mab monoclonal antibody, BiTE bispecific T-cell …
clinical applications. … BsAb bispecific antibody, Mab monoclonal antibody, BiTE bispecific T-cell …
Antibody-based immunotherapeutics and use of convalescent plasma to counter COVID-19: advances and prospects
… This review provides the current status of the development of … into clinical use for prophylactic
and therapeutic purposes … can be identified, and therapeutic monoclonal antibody can be …
and therapeutic purposes … can be identified, and therapeutic monoclonal antibody can be …
[HTML][HTML] Extremely potent human monoclonal antibodies from COVID-19 convalescent patients
… Summary Human monoclonal antibodies are safe, preventive, and therapeutic tools that
can be rapidly developed to help restore the massive health and economic disruption caused …
can be rapidly developed to help restore the massive health and economic disruption caused …
ImmunoPET: concept, design, and applications
W Wei, ZT Rosenkrans, J Liu, G Huang, QY Luo… - Chemical …, 2020 - ACS Publications
… the superior targeting specificity of monoclonal antibody (mAb) and … strategies and their
preclinical and clinical applications. We also … In the last part of the review, we discuss practical …
preclinical and clinical applications. We also … In the last part of the review, we discuss practical …