[HTML][HTML] Predicting bioavailability of monoclonal antibodies after subcutaneous administration: open innovation challenge
M Sánchez-Félix, M Burke, HH Chen… - Advanced drug delivery …, 2020 - Elsevier
… Based on our review of the available models, while there are promising advances in
modelling capability, particularly in relation to rate of absorption, none are yet capable of …
modelling capability, particularly in relation to rate of absorption, none are yet capable of …
Anifrolumab, a monoclonal antibody to the type I interferon receptor subunit 1, for the treatment of systemic lupus erythematosus: an overview from clinical trials
Y Tanaka, R Tummala - Modern Rheumatology, 2021 - academic.oup.com
… Based on the results of the review, revised restricted medication rules for the use of NSAIDs
and other medications were agreed on with an external steering committee for the TULIP …
and other medications were agreed on with an external steering committee for the TULIP …
Recent progress in aptamer discoveries and modifications for therapeutic applications
… of monoclonal antibodies. They are attracting great attention in diverse clinical translations
on account of their … This Review aims to provide a deeper understanding of the research and …
on account of their … This Review aims to provide a deeper understanding of the research and …
Molecularly imprinted synthetic antibodies: from chemical design to biomedical applications
… Billions of dollars are invested into the monoclonal antibody … in bio-related applications,
this review also pointed out the … antibodies, so as to jointly lead the future development trend. …
this review also pointed out the … antibodies, so as to jointly lead the future development trend. …
The therapeutic potential of nanobodies
I Jovčevska, S Muyldermans - BioDrugs, 2020 - Springer
… In this review, we briefly outline the beneficial properties of camelid nanobodies in … than
classical monoclonal antibodies, which is obviously crucial for therapeutic applications [39, 61]. …
classical monoclonal antibodies, which is obviously crucial for therapeutic applications [39, 61]. …
Bispecific antibodies for multiple myeloma: a review of targets, drugs, clinical trials, and future directions
C Caraccio, S Krishna, DJ Phillips… - Frontiers in …, 2020 - frontiersin.org
… In this review, we outline these advances, focusing on BsAb drugs, their targets, and their …
Since no immunomodulatory BsAbs are currently in clinical trials for MM, this review will …
Since no immunomodulatory BsAbs are currently in clinical trials for MM, this review will …
Antibody conjugates-recent advances and future innovations
… conjugates, these entities were met with limited clinical success. This review summarizes
the … consideration for both monoclonal antibody therapeutics and ADC therapeutics [23]. Fc-…
the … consideration for both monoclonal antibody therapeutics and ADC therapeutics [23]. Fc-…
Antibody-Drug Conjugates: A promising breakthrough in cancer therapy
S Parit, A Manchare, AD Gholap, P Mundhe… - International Journal of …, 2024 - Elsevier
… This review provides a comprehensive examination of the … their design, mechanisms of action,
and clinical applications. The … landscape of monoclonal antibody-mediated therapy. These …
and clinical applications. The … landscape of monoclonal antibody-mediated therapy. These …
Structure, function, and therapeutic use of IgM antibodies
BA Keyt, R Baliga, AM Sinclair, SF Carroll… - Antibodies, 2020 - mdpi.com
… Here, we review the progress and the therapeutic potential for this class of antibodies, as …
agent consisting of a murine IgM monoclonal antibody labeled with technetium-99m ( 99m Tc). …
agent consisting of a murine IgM monoclonal antibody labeled with technetium-99m ( 99m Tc). …
A monoclonal antibody for malaria prevention
MR Gaudinski, NM Berkowitz, AH Idris… - … England Journal of …, 2021 - Mass Medical Soc
… The NIH institutional review board reviewed and approved the trial protocol. All participants
… a pharmacokinetic profile aligned with potential clinical use across a variety of settings. …
… a pharmacokinetic profile aligned with potential clinical use across a variety of settings. …