[HTML][HTML] Predicting bioavailability of monoclonal antibodies after subcutaneous administration: open innovation challenge

M Sánchez-Félix, M Burke, HH Chen… - Advanced drug delivery …, 2020 - Elsevier
… Based on our review of the available models, while there are promising advances in
modelling capability, particularly in relation to rate of absorption, none are yet capable of …

Anifrolumab, a monoclonal antibody to the type I interferon receptor subunit 1, for the treatment of systemic lupus erythematosus: an overview from clinical trials

Y Tanaka, R Tummala - Modern Rheumatology, 2021 - academic.oup.com
… Based on the results of the review, revised restricted medication rules for the use of NSAIDs
and other medications were agreed on with an external steering committee for the TULIP …

Recent progress in aptamer discoveries and modifications for therapeutic applications

S Ni, Z Zhuo, Y Pan, Y Yu, F Li, J Liu… - … Applied Materials & …, 2020 - ACS Publications
… of monoclonal antibodies. They are attracting great attention in diverse clinical translations
on account of their … This Review aims to provide a deeper understanding of the research and …

Molecularly imprinted synthetic antibodies: from chemical design to biomedical applications

J Xu, H Miao, J Wang, G Pan - Small, 2020 - Wiley Online Library
… Billions of dollars are invested into the monoclonal antibody … in bio-related applications,
this review also pointed out the … antibodies, so as to jointly lead the future development trend. …

The therapeutic potential of nanobodies

I Jovčevska, S Muyldermans - BioDrugs, 2020 - Springer
… In this review, we briefly outline the beneficial properties of camelid nanobodies in … than
classical monoclonal antibodies, which is obviously crucial for therapeutic applications [39, 61]. …

Bispecific antibodies for multiple myeloma: a review of targets, drugs, clinical trials, and future directions

C Caraccio, S Krishna, DJ Phillips… - Frontiers in …, 2020 - frontiersin.org
… In this review, we outline these advances, focusing on BsAb drugs, their targets, and their
Since no immunomodulatory BsAbs are currently in clinical trials for MM, this review will …

Antibody conjugates-recent advances and future innovations

D Leung, JM Wurst, T Liu, RM Martinez… - Antibodies, 2020 - mdpi.com
… conjugates, these entities were met with limited clinical success. This review summarizes
the … consideration for both monoclonal antibody therapeutics and ADC therapeutics [23]. Fc-…

Antibody-Drug Conjugates: A promising breakthrough in cancer therapy

S Parit, A Manchare, AD Gholap, P Mundhe… - International Journal of …, 2024 - Elsevier
… This review provides a comprehensive examination of the … their design, mechanisms of action,
and clinical applications. The … landscape of monoclonal antibody-mediated therapy. These …

Structure, function, and therapeutic use of IgM antibodies

BA Keyt, R Baliga, AM Sinclair, SF Carroll… - Antibodies, 2020 - mdpi.com
… Here, we review the progress and the therapeutic potential for this class of antibodies, as …
agent consisting of a murine IgM monoclonal antibody labeled with technetium-99m ( 99m Tc). …

A monoclonal antibody for malaria prevention

MR Gaudinski, NM Berkowitz, AH Idris… - … England Journal of …, 2021 - Mass Medical Soc
… The NIH institutional review board reviewed and approved the trial protocol. All participants
… a pharmacokinetic profile aligned with potential clinical use across a variety of settings. …