Biology drives the discovery of bispecific antibodies as innovative therapeutics

S Nie, Z Wang, M Moscoso-Castro… - … therapeutics, 2020 - academic.oup.com
… In this review article, we introduce a system that classifies … of new era of monoclonal antibody
(mAb)-based therapy [1]. … to fulfill a particular clinical application. Small variations, such as …

[HTML][HTML] European Headache Federation guideline on the use of monoclonal antibodies targeting the calcitonin gene related peptide pathway for migraine prevention …

S Sacco, FM Amin, M Ashina, L Bendtsen… - The journal of headache …, 2022 - Springer
… The landscape of migraine prevention has experienced relevant changes since the
introduction of the monoclonal antibodies (mAbs) targeting the calcitonin gene-related (CGRP) …

Recent strategies towards the surface modification of liposomes: an innovative approach for different clinical applications

AA Khan, KS Allemailem, SA Almatroodi, A Almatroudi… - 3 Biotech, 2020 - Springer
… This review article summarizes briefly the preparation of … their clinical applications especially
as drug delivery system. … been applied to use monoclonal antibodies or their fragments to …

[HTML][HTML] Therapeutic applications of nucleic acid aptamers in microbial infections

S Afrasiabi, M Pourhajibagher, R Raoofian… - Journal of Biomedical …, 2020 - Springer
… -based affinity ligands, replacing monoclonal antibodies. The aptamer-based systems …
review is on the therapeutic applications of aptamers in infections. In this regard, an introduction

Structure of CD20 in complex with the therapeutic monoclonal antibody rituximab

L Rougé, N Chiang, M Steffek, C Kugel, TI Croll, C Tam… - Science, 2020 - science.org
monoclonal antibodies for the treatment of malignancies and autoimmune disorders but whose
structure and function are unknown. Rituximab (RTX) has been in clinical use … In summary

Mesoporous silica nanoparticles: Synthesis methods and their therapeutic use-recent advances

M Ghaferi, M Koohi Moftakhari Esfahani… - Journal of Drug …, 2021 - Taylor & Francis
… This literature review provides an overview of MSNPs, in terms of their preparation, surface
… [Citation219] synthesised TRC105 (a human/ murine chimeric IgG1 monoclonal antibody

[HTML][HTML] An insight into FDA approved antibody-drug conjugates for cancer therapy

JTW Tong, PWR Harris, MA Brimble, I Kavianinia - Molecules, 2021 - mdpi.com
… ” of cancer therapy, and are composed of three key elements: a monoclonal antibody that
selectively … In this review, we aim to provide a brief and up to date overview of each of the FDA …

Treatment-Related Adverse Events of Subcutaneous Monoclonal Antibodies in Cancer Patients: A Systemic Review and Meta-Analysis

B Zhang, H Cui, D Huang, S Li - Available at SSRN 4869105 - papers.ssrn.com
… Nowadays, here is a lack of systematic and comprehensive guidelines for the management
of clinical applications and pharmacy services for the safe use and monitoring of …

[HTML][HTML] Receptor-binding domain-specific human neutralizing monoclonal antibodies against SARS-CoV and SARS-CoV-2

F Yu, R Xiang, X Deng, L Wang, Z Yu, S Tian… - … and Targeted Therapy, 2020 - nature.com
… This review summarizes the structure and function of RBD and RBD-specific NMAbs against
… an ideal mAb pair for virus targeting to avoid immune escape in future clinical applications. …

[HTML][HTML] Progressing nanotechnology to improve targeted cancer treatment: overcoming hurdles in its clinical implementation

M Chehelgerdi, M Chehelgerdi, OQB Allela… - Molecular cancer, 2023 - Springer
… In this review, we analyze some of the authorized … have undergone clinical trials or have
been approved for clinical use in … The key advantage of monoclonal antibodies lies in their high …