[HTML][HTML] In vivo fluorescence imaging: success in preclinical imaging paves the way for clinical applications

A Refaat, ML Yap, G Pietersz, APG Walsh… - Journal of …, 2022 - Springer
review, we discuss the latest advances in in vivo fluorescence imaging technologies, NIR
fluorescent probes, and current and future clinical applications… or monoclonal antibodies (mAb) …

Anti-CGRP monoclonal antibodies for migraine prevention: a systematic review and likelihood to help or harm analysis

K Drellia, L Kokoti, CI Deligianni… - …, 2021 - journals.sagepub.com
… The selection of anti-CGRP mAbs comparators was based on three … of their clinical evaluation
program, the timing of clinical testing, and finally their frequency of use in current clinical

[HTML][HTML] Phage display technology as a powerful platform for antibody drug discovery

K Nagano, Y Tsutsumi - Viruses, 2021 - mdpi.com
… Here, we review the importance of … monoclonal antibodies with high specificity and affinity
to target molecules were expected to be used as magic bullets for various clinical applications […

Interleukin-6 cytokine: An overview of the immune regulation, immune dysregulation, and therapeutic approach

M Aliyu, FT Zohora, AU Anka, K Ali, S Maleknia… - International …, 2022 - Elsevier
… Tocilizumab is a humanized monoclonal antibody (mAb) that targets IL-6R as outlined …
Sirukumab (formerly known as CNTO 136) is a human anti-IL-6 monoclonal antibody developed …

Cell membrane-coated mimics: a methodological approach for fabrication, characterization for therapeutic applications, and challenges for clinical translation

V Chugh, K Vijaya Krishna, A Pandit - ACS nano, 2021 - ACS Publications
… In this review, we focus on providing a detailed insight into the … an overview of different cell
types, their inherent biological properties, and suitability for specific therapeutic applications

Broad neutralization of SARS-related viruses by human monoclonal antibodies

AZ Wec, D Wrapp, AS Herbert, DP Maurer… - Science, 2020 - science.org
… Studies of convalescent sera and a limited number of monoclonal antibodies (mAbs) have
revealed limited to no cross-neutralizing activity, demonstrating that conserved antigenic sites …

Antibody and cellular therapies for treatment of covid-19: a living systematic review and network meta-analysis

RAC Siemieniuk, JJ Bartoszko, JPD Martinez, E Kum… - Bmj, 2021 - bmj.com
… the use of antiviral monoclonal antibodies of covid-19.… therapeutic applications in the
treatment of congenital and acquired diseases,8 one can, in the absence of clear evidence for use

Viral vector‐based gene therapies in the clinic

Z Zhao, AC Anselmo, S Mitragotri - … & translational medicine, 2022 - Wiley Online Library
… 13 approved products and their clinical applications. We have … Here, we provide an overview
of clinical advances of viral … protein, VRC07 human monoclonal antibody, are studied in …

[HTML][HTML] Potential therapeutic options for COVID-19: an update on current evidence

Z Niknam, A Jafari, A Golchin, F Danesh Pouya… - European journal of …, 2022 - Springer
… In this review, the current evidence of potential therapeutic … on the antibody include neutralizing
monoclonal antibodies, and … These therapeutic approachs and their clinical application

[HTML][HTML] Fc-engineered antibody therapeutics with improved anti-SARS-CoV-2 efficacy

R Yamin, AT Jones, HH Hoffmann, A Schäfer, KS Kao… - Nature, 2021 - nature.com
… neutralizing monoclonal antibodies that are in clinical usereview information Nature thanks
Patrick Wilson and the other, anonymous, reviewers for their contribution to the peer review