Landscape of circulating tumour DNA in metastatic breast cancer
AA Davis, S Jacob, L Gerratana, AN Shah, F Wehbe… - …, 2020 - thelancet.com
… The goals of the analysis were to identify the landscape of ctDNA across pathological
subtypes, to evaluate the prevalence of clinically actionable alterations, to compare blood and …
subtypes, to evaluate the prevalence of clinically actionable alterations, to compare blood and …
Association of circulating tumor DNA with disease-free survival in breast cancer: a systematic review and meta-analysis
C Cullinane, C Fleming, DP O'Leary… - JAMA network …, 2020 - jamanetwork.com
… as a prognostic marker can be applied to both early and metastatic breast cancer disease
as suggested by subgroup analysis in this study. Another potential benefit of ctDNA is that it …
as suggested by subgroup analysis in this study. Another potential benefit of ctDNA is that it …
[HTML][HTML] Circulating tumor DNA in neoadjuvant-treated breast cancer reflects response and survival
MJM Magbanua, LB Swigart, HT Wu, GL Hirst, C Yau… - Annals of …, 2021 - Elsevier
… serial circulating tumor DNA (ctDNA) testing for predicting pCR and risk of metastatic recurrence.
… In summary, our study shows promise that early response prediction by highly sensitive …
… In summary, our study shows promise that early response prediction by highly sensitive …
Circulating tumour DNA analysis to direct therapy in advanced breast cancer (plasmaMATCH): a multicentre, multicohort, phase 2a, platform trial
NC Turner, B Kingston, LS Kilburn… - The Lancet …, 2020 - thelancet.com
… The high sensitivity of ctDNA testing for tissue mutations calls into question the need … ctDNA
results, within the pretreated metastatic breast cancer patient population studied. This study …
results, within the pretreated metastatic breast cancer patient population studied. This study …
Circulating tumor DNA as a dynamic biomarker of response to palbociclib and fulvestrant in metastatic breast cancer patients
L Darrigues, JY Pierga, A Bernard-Tessier… - Breast Cancer …, 2021 - Springer
… early changes of circulating tumor DNA (ctDNA) levels … study were to evaluate the relationship
between ctDNA detection and variation from baseline (bsl) to D15 and D30 with the tumor …
between ctDNA detection and variation from baseline (bsl) to D15 and D30 with the tumor …
Current status of circulating tumor cells, circulating tumor DNA, and exosomes in breast cancer liquid biopsies
M Tellez-Gabriel, E Knutsen, M Perander - International Journal of …, 2020 - mdpi.com
… of ctDNA in breast cancer. There are two fundamental strategies to analyze ctDNA: (1)
Quantification of total cfDNA based on the notion that cancer cells release more DNA than healthy …
Quantification of total cfDNA based on the notion that cancer cells release more DNA than healthy …
Circulating tumor DNA after neoadjuvant chemotherapy in breast cancer is associated with disease relapse
F Cailleux, E Agostinetto, M Lambertini… - JCO Precision …, 2022 - ascopubs.org
… Detection of circulating tumor DNA (ctDNA) after neoadjuvant … stage breast cancer may
allow for early detection of relapse. In this study, we analyzed ctDNA using a personalized, tumor-…
allow for early detection of relapse. In this study, we analyzed ctDNA using a personalized, tumor-…
Assessing tumor heterogeneity using ctDNA to predict and monitor therapeutic response in metastatic breast cancer
F Ma, Y Guan, Z Yi, L Chang, Q Li… - … journal of cancer, 2020 - Wiley Online Library
… that tumor heterogeneity can be noninvasively assessed through circulating tumor DNA (ctDNA).14-…
treatment outcome using tumor heterogeneity in ctDNA of metastatic breast cancer. …
treatment outcome using tumor heterogeneity in ctDNA of metastatic breast cancer. …
[HTML][HTML] Circulating breast-derived DNA allows universal detection and monitoring of localized breast cancer
J Moss, A Zick, A Grinshpun, E Carmon, M Maoz… - Annals of …, 2020 - Elsevier
… Circulating tumor DNA (ctDNA), identified based on the presence of somatic mutations, can
… that breast DNA could be detected in the circulation of patients with metastatic breast cancer, …
… that breast DNA could be detected in the circulation of patients with metastatic breast cancer, …
Serial analysis of circulating tumor cells in metastatic breast cancer receiving first-line chemotherapy
MJM Magbanua, LH Hendrix, T Hyslop… - … the National Cancer …, 2021 - academic.oup.com
… that the detection of circulating tumor DNA (ctDNA) in blood is strongly associated with
poor prognosis (15,16). Contemporaneous analysis of CTCs and ctDNA in MBC have been …
poor prognosis (15,16). Contemporaneous analysis of CTCs and ctDNA in MBC have been …