Treatment for liver cancer: From sorafenib to natural products

S Man, C Luo, M Yan, G Zhao, L Ma, W Gao - European journal of …, 2021 - Elsevier
Hepatocellular carcinoma (HCC) as the most common form of … ) 7 is further identified to be
a potential target suppressed … In summary, we have over-viewed the advancement in liver

Predicting therapeutic drugs for hepatocellular carcinoma based on tissue-specific pathways

L Yu, M Wang, Y Yang, F Xu, X Zhang… - PLoS Computational …, 2021 - journals.plos.org
… By using the cancer cell line data in the database, we … [10] identified 22 liver cancer–related
enhancer single-… In this study, we proposed an approach to identify potential drugs for the …

Differential effectiveness of tyrosine kinase inhibitors in 2D/3D culture according to cell differentiation, p53 status and mitochondrial respiration in liver cancer cells

MA Rodríguez-Hernández, R Chapresto-Garzón… - Cell Death & …, 2020 - nature.com
… -line therapies in patients with advanced hepatocellular carcinoma (HCC). … SNU449, HLF,
and HLE liver cancer cell lines that express … classification of HCC has identified a poor survival …

Improving the efficacy of liver cancer immunotherapy: the power of combined preclinical and clinical studies

GS Feng, KL Hanley, Y Liang, X Lin - Hepatology, 2021 - Wiley Online Library
Hepatocellular carcinoma (HCC) is a most deadly malignant … liver cancer by blocking identified
oncogenic pathways is … grown subcutaneously from the same cell line were suppressed …

A powerful drug combination strategy targeting glutamine addiction for the treatment of human liver cancer

H Jin, S Wang, EA Zaal, C Wang, H Wu, A Bosma… - Elife, 2020 - elifesciences.org
… A total of 66 named metabolites were identified and … study showed that the vast majority of
liver cancer cell linesliver cancer cell lines were established from hepatocellular carcinoma

Emerging therapies for hepatocellular carcinoma (HCC)

E Chakraborty, D Sarkar - Cancers, 2022 - mdpi.com
liver cancer, also known as Hepatocellular carcinoma (HCC)… in HCC cell line HepG2 compared
to normal liver cells HL-… classification to identify the best possible treatment strategy. The …

[HTML][HTML] Recent progress in treatment of hepatocellular carcinoma

Z Chen, H Xie, M Hu, T Huang, Y Hu… - … journal of cancer …, 2020 - ncbi.nlm.nih.gov
… HCC patients can be identified for diagnosis and treatment, … flora will also be a potential
means of treating liver cancer. … which cultured human hepatoblastoma cell line HepG2 C3A in …

The curious case of the HepG2 cell line: 40 years of expertise

VA Arzumanian, OI Kiseleva… - International journal of …, 2021 - mdpi.com
… most studied hepatic tumor cell lines. Characteristics for all … cell line was mistakenly labeled
as hepatocellular carcinoma (… Promoter mutations have been identified as the most frequent …

Molecular docking, anti-proliferative activity and induction of apoptosis in human liver cancer cells treated with androstane derivatives: Implication of PI3K/AKT/mTOR …

SW Kattan, MS Nafie, GA Elmgeed, W Alelwani… - The Journal of Steroid …, 2020 - Elsevier
… , and it is now increasingly identified at a much earlier stage as a … against hepatocellular
carcinoma HepG2 cell line using different … and selectivity of compound 4 on liver cancer cell line. …

Immunotherapies for hepatocellular carcinoma

JM Llovet, F Castet, M Heikenwalder… - Nature reviews Clinical …, 2022 - nature.com
Liver cancer, more specifically hepatocellular carcinoma (… the immune TME is needed to
identify mechanisms that can be … in the liver parenchyma 96 , which probably affects the hepatic