Shared heritability of human face and brain shape

S Naqvi, Y Sleyp, H Hoskens, K Indencleef… - Nature …, 2021 - nature.com
… To more directly test for sharing of genetic effects between brain and face shape, we
intersected the 472 loci described in this study with 203 loci previously associated with face shape …

[HTML][HTML] Structural brain imaging studies offer clues about the effects of the shared genetic etiology among neuropsychiatric disorders

NV Radonjić, JL Hess, P Rovira, O Andreassen… - Molecular …, 2021 - nature.com
… (SMDs) in regional brain volume and cortical thickness between … brain regions for:
attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder (ASD), bipolar disorder

[HTML][HTML] The genetic architecture of the human thalamus and its overlap with ten common brain disorders

T Elvsåshagen, A Shadrin, O Frei… - Nature …, 2021 - nature.com
… between thalamus volumes and ten neurological and psychiatric disorders. Further … of brain
disorders and the pleiotropic loci identified by our analyses could inform such experiments. …

Risk in relatives, heritability, SNP-based heritability, and genetic correlations in psychiatric disorders: a review

BML Baselmans, L Yengo, W van Rheenen… - Biological Psychiatry, 2021 - Elsevier
… Since these methods are relatively new, we estimated the SNP-based heritability of all
major psychiatric disorders using publicly available GWAS summary statistics (https://www.med.…

[HTML][HTML] The reliability and heritability of cortical folds and their genetic correlations across hemispheres

F Pizzagalli, G Auzias, Q Yang, SR Mathias… - Communications …, 2020 - nature.com
… of brain structural and functional differences are important to identify as potential risk factors
for heritable brain diseases… 1 consortium, have identified common genetic variants that have …

Partitioning heritability analyses unveil the genetic architecture of human brain multidimensional functional connectivity patterns

J Feng, C Chen, Y Cai, Z Ye, K Feng, J Liu… - Human brain …, 2020 - Wiley Online Library
study were significantly heritable, making them appropriate targets for more specific genetic
analyses… ie, enrichment) to the heritability of multidimensional functional connectivity patterns…

Dissecting the shared genetic basis of migraine and mental disorders using novel statistical tools

S Bahrami, G Hindley, BS Winsvold, KS O'Connell… - Brain, 2022 - academic.oup.com
analyses provided insights into putative shared mechanisms, our spatiotemporal gene-expression
analysis identified brain … these processes may impact disorder risk. Interestingly, …

[HTML][HTML] The genetic architecture of human brainstem structures and their involvement in common brain disorders

T Elvsåshagen, S Bahrami, D van der Meer… - Nature …, 2020 - nature.com
disorders. In additional clinical data from 5062 individuals with common brain disorders and
… , bipolar disorder, multiple sclerosis, mild cognitive impairment, dementia, and Parkinson’s …

[HTML][HTML] Genome-wide association study reveals new insights into the heritability and genetic correlates of developmental dyslexia

A Gialluisi, TFM Andlauer, N Mirza-Schreiber… - Molecular …, 2021 - nature.com
… When we analysed partitioned heritability by sets of specifically overexpressed genes in 13
different brain regions available in the GTEx database (see “Methods” section), we observed …

Genetic correlates of socio-economic status influence the pattern of shared heritability across mental health traits

AT Marees, DJA Smit, A Abdellaoui, MG Nivard… - Nature human …, 2021 - nature.com
… of shared heritability. Twin and family studies have shown that genetic risk factors contribute
substantially to the risk of developing a mental health disorder, with heritability estimates …