Quantitative measures of crystalline fenofibrate in amorphous solid dispersion formulations by X-ray microscopy
JP Neilly, L Yin, SE Leonard, PJA Kenis… - … of Pharmaceutical …, 2020 - Elsevier
… and quantitative data analysis using basic image analysis tools. The technique is nondestructive,
… Quantitation of crystalline fenofibrate consisted of counting the number of voxels with …
… Quantitation of crystalline fenofibrate consisted of counting the number of voxels with …
Surface characterization of pharmaceutical solids
… In the current review, the analytical techniques have been … -point BET method for rapid
determination of SSA regardless … , deliquescence, amorphous–crystalline transformation and …
determination of SSA regardless … , deliquescence, amorphous–crystalline transformation and …
Identification and quantification techniques of polymorphic forms-A review
… solid-state techniques for detection and quantification … pharmaceutical products. Therefore,
in the context of monitoring and controlling polymorphism, the choice of analytical technique …
in the context of monitoring and controlling polymorphism, the choice of analytical technique …
Analytical techniques for structural characterization of proteins in solid pharmaceutical forms: An overview
… (amorphous/crystalline) of lyophilized proteins. Moreover, recently developed methods
based on mass spectrometry, such as solid… it is difficult to perform quantification analysis [181,189]…
based on mass spectrometry, such as solid… it is difficult to perform quantification analysis [181,189]…
Solid-state analysis of amorphous solid dispersions: Why DSC and XRPD may not be regarded as stand-alone techniques
S Dedroog, T Pas, B Vergauwen, C Huygens… - … of Pharmaceutical and …, 2020 - Elsevier
… phase behavior can refer to both amorphous-amorphous and amorphous-crystalline phase
… In this paper, we will highlight the two most commonly applied analytical techniques for solid-…
… In this paper, we will highlight the two most commonly applied analytical techniques for solid-…
… , powder X-ray diffraction, and solid-state nuclear magnetic resonance spectroscopy for measuring crystallinity in amorphous solid dispersions-application to drug-in …
TW Jarrells, EJ Munson - Journal of Pharmaceutical Sciences, 2022 - Elsevier
… This work compared various analytical methods and techniques for quantifying endogenous
crystallinity in an ASD. Annealing-induced crystallinity was analyzed using various DSC, …
crystallinity in an ASD. Annealing-induced crystallinity was analyzed using various DSC, …
Characterization of amorphous solid dispersions and identification of low levels of crystallinity by transmission electron microscopy
M S'ari, H Blade, S Cosgrove… - … Pharmaceutics, 2021 - ACS Publications
… and has recently emerged as a useful analytical technique to study ASDs. Electron diffraction
and … scanning techniques to provide a more easily quantifiable measure of crystallization. …
and … scanning techniques to provide a more easily quantifiable measure of crystallization. …
Quantifying Micromolar Crystallinity in Pharmaceutical Materials Utilizing 19F Solid-State NMR
… LOD and the limit of quantification (LOQ) for analytical procedures that exhibit baseline noise,
respectively. Using this specification, the LOD and LOQ of the PXRD method in the current …
respectively. Using this specification, the LOD and LOQ of the PXRD method in the current …
[HTML][HTML] Quantitative analysis of amorphous form in indomethacin binary polymorphic mixtures using infrared spectroscopy analytical techniques combined with …
M Liu, J Liu, Q Wang, P Song, H Li, Y Qin, S Wu… - Arabian Journal of …, 2023 - Elsevier
… In general, these two solid analysis techniques were suitable for the quantitative analysis of
… optimal quantitative model established by NIR analysis technology had lower LOD and LOQ …
… optimal quantitative model established by NIR analysis technology had lower LOD and LOQ …
A novel technique to characterize and quantify crystalline and amorphous matter in complex sugar mixtures
P Verma, NG Shah, SM Mahajani - Food Analytical Methods, 2020 - Springer
… In this article, we discuss the existing techniques and their … quantification of individual sugars
in the amorphous and crystalline forms will be discussed in detail. The proposed method is …
in the amorphous and crystalline forms will be discussed in detail. The proposed method is …