… Andexanet-Alfa Andexanet alfa (andexanet) is a recombinant FXa variant without … Four-factor
prothrombin complex concentrate for the treatment of oral factor Xa inhibitor-associated …

… reversal agent. The recent approved agent for factor Xa inhibitor reversal, andexanet alfa, …
published trials utilizing andexanet alfa in humans for anticoagulation reversal. The results …

… andexanet alfa was recently approved as a specific reversal … elect to administer 4-factor
prothrombin complex concentrate (4F… Anticoagulation Forum suggests factor Xa inhibitor reversal …

… Andexanet alfa (AA), a factor Xa-inhibitor (FXi) reversal agent, is given as a bolus followed
by a 2-hour … -inhibitors (FXi) have emerged as an oral anticoagulant with similar efficacy and …

… regarding optimal reversal agent for factor Xa-inhibitors is … both administered for FXa-inhibitor
associated ICH. The results … In patients anticoagulated with a FXaI who present with acute …

… of PCC in factor Xa inhibitor associated bleeding by two … assessment criteria following
anticoagulation reversal with a … when indirectly compared to andexanet alfa. A retrospective …

… Andexanet alfa is a molecularly modified factor Xa decoy … for factor Xa inhibitors 3 that
competitively binds to factor Xa … suggest that andexanet alfa reverses anticoagulation in a …

… specifically designed to reverse the anticoagulant effects of … in 2019 as the first specific
reversal agent for rivaroxaban- or … the Andexanet Alfa, a Novel Antidote to the Anticoagulation …

… Factor Xa (fXa) inhibitors are a novel class of anticoagulants … superiority of andexanet alfa,
4-factor prothrombin complex … reversing fXa inhibitor–associated major bleeding. Although …

… 4PCC or specific reversal agents (idarucizumab or andexanet alfa) is associated with
considerable mortality. Thromboembolic events occur more frequently with andexanet than with …