[HTML][HTML] Pathogenesis and current treatment strategies of hepatocellular carcinoma

D Tümen, P Heumann, K Gülow, CN Demirci… - Biomedicines, 2022 - mdpi.com
… with enhancer of zeste homologue 2 (EZH2) to suppress its … (lnc-MVIH) activates angiogenesis
by promoting tumor growth and … In terms of liver homeostasis and regeneration in adults, it …

Hepatocellular carcinoma organoid co-cultures mimic angiocrine crosstalk to generate inflammatory tumor microenvironment

JTC Lim, LG Kwang, NCW Ho, CCM Toh, NSH Too… - Biomaterials, 2022 - Elsevier
… We report that in the absence of exogeneous angiogenic factors typically added to endothelial
… The rationale for this was to reduce masking and interference of the potential angiocrine-…

HIF-2α-targeted interventional chemoembolization multifunctional microspheres for effective elimination of hepatocellular carcinoma

M Chen, G Shu, X Lv, X Xu, C Lu, E Qiao, S Fang… - Biomaterials, 2022 - Elsevier
… ; 1.8% maintenance) by a mask, then a 2–3 cm was made along … it also could inhibit tumor
angiogenesis by down-regulating … angiogenesis and cell regeneration, and then produced a …

Three-dimensional cell culture models of hepatocellular carcinoma—A review

I Ayvaz, D Sunay, E Sariyar, E Erdal… - … of gastrointestinal cancer, 2021 - Springer
… Besides their role in liver development and regeneration, HSCs are also important for …
Also, the pro-angiogenic microenvironment is created by the interaction between HCC cells and …

[HTML][HTML] The angiopoietin/Tie2 pathway in hepatocellular carcinoma

B Vanderborght, S Lefere, HV Vlierberghe… - Cells, 2020 - mdpi.com
… inhibition attenuated Ang-2 expression, as well as inhibited tumor angiogenesis and growth
in a subcutaneous syngeneic HCC mouse model. Therefore, although further exploration of …

[HTML][HTML] Novel risk model based on angiogenesis-related lncRNAs for prognosis prediction of hepatocellular carcinoma

S Xie, J Zhong, Z Zhang, W Huang, X Lin, Y Pan… - Cancer Cell …, 2023 - Springer
Hepatocellular carcinoma (HCC) is a major cause of cancer-related death due to early
metastasis or recurrence. Tumor angiogenesis … in tumor angiogenesis. Here, we established an …

A concise review of VEGF, PDGF, FGF, Notch, angiopoietin, and HGF signalling in tumor angiogenesis with a focus on alternative approaches and future directions

S Vimalraj - International Journal of Biological Macromolecules, 2022 - Elsevier
… (OC), non-small cell lung cancer (NSCLC), and hepatocellular carcinoma (HCC) are known
angiogenesis (kidney development, liver disease, and inflammatory neural diseases) [2], [72]…

[HTML][HTML] Identification and validation of the angiogenic genes for constructing diagnostic, prognostic, and recurrence models for hepatocellular carcinoma

J Zhu, B Tang, J Li, Y Shi, M Chen, X Lv… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
Angiogenesis is required for tissue repair, remodeling in physiological processes such as
reproduction, embryo development and wound healing, and it is a hallmark of disease states …

[HTML][HTML] Molecular and functional roles of microRNAs in the progression of hepatocellular carcinoma—a review

K Oura, A Morishita, T Masaki - International Journal of Molecular …, 2020 - mdpi.com
multiple cell types that make up the liver interact via various signaling factors. Although the
mechanisms of liver regeneration in the injured liver … cells to secrete angiogenic molecules …

[HTML][HTML] Advances in recellularization of decellularized liver grafts with different liver (stem) cells: towards clinical applications

B Toprakhisar, CM Verfaillie, M Kumar - Cells, 2023 - mdpi.com
liver, enhancing parenchymal regeneration via the prevention of apoptosis, stimulation of
hepatocyte proliferation and angiogenesis, and … been suggested by several groups to mask the …