… Delivery of ghrelin receptor antagonists results in … ghrelin, or the GHSR1a antagonist
JMV2959, and connected it to a cannula aimed unilaterally at the DMH of adult male C57BLJ6 mice …

… increased at 3 hours and 6 hours post injection, leading to an increase in total energy
intake ((6)). Prior to injecting ghrelin and its receptor antagonist into the lPBN, rats had similar …

… To gain insights of the putative mechanisms that abrogate the … GHR KO mice to increase
food intake in response to ghrelin, we … Reduced expression of NPY and ghrelin receptor in the …

… In circulation, LEAP-2 displays an inverse pattern as to ghrelin; it increases with food intake
… reduced ghrelin levels of the mice under chronic food restriction, but not in the mice under ad …

… To validate the absence of CB1R activity in CB1R-null mice, we measured the acute food
intake … , in which the CB1R antagonists SR141716A and oleoylethanolamine reduced plasma …

… that differs from the complex bound with agonists or antagonists 35,36,37 (PDB ID: … antagonist
in the ghrelin receptor 30 (Fig. 2b). The antagonist compound 21-bound ghrelin receptor …

… food intake and body weight gain in mice treated with MIA-690, we did not find any effect of
the GHRH antagonist … that GHRHKO mice are more sensitive to ghrelin-induced food intake …

… In summary we here show that ghrelin, alcohol and amphetamine increase … reduced by
ghrelin receptor antagonism. Dopamine D 1 receptor with the VTA regulate the ability of ghrelin …

… assessed delayed ghrelin-induced food intake in WT mice in … /4 receptor ligand MT-II, which
competes with AgRP action. We found that mice ICV injected with MT-II showed a decreased …

… of the ghrelin signal with infusions of L-RNA aptamers in diet-induced obese mice significantly
reduced food intake and body weight gain, … , indicating that antagonism of ghrelin-induced …