… identified antagonist and an inverse agonist of the growth hormone … receptor (GHSR).
GHSR's other well-known endogenous ligand, acyl-ghrelin, increases food intake, body weight, …

… Recent elucidation of the crystal structure of the ghrelin receptor … receptor antagonist to
normal male and female mice is … , was observed to reduce food intake in male mice (Figure 4 …

… mice model of 60% CR and found that the administration of [d-Lys3]-GHRP-6 (a ghrelin receptor
antagonist) in mice under 60% CR reduced … CRF-R activation decreases food intake, 39-…

… decreases short- and long-term food intake and body weight and blocks short-term
ghrelin-stimulated feeding in male rats. … ghrelin, rather than a GHSR nonendogenous antagonist, …

… ghrelin receptors are found in fish (20 species), and ghrelin … effect of ghrelin on NPY / AgRP
neurons is limited to mice fed … or obesity), the antagonism of ghrelin function can promote …

… We monitored body weights and food intake of individually-… that homozygous mice exhibited
lower body weights compared … production by LEAP-2 occurs through GHSR antagonism or a …

… investigated the effect of ghrelin receptor inhibition on the … Although feed intake was
unaffected, the body weight gain of … homeostasis of mice under the condition of a high-fat dietary. …

… total ghrelin blood concentrations and food intake in rats. … that the GHS-R1A antagonism
attenuated the anticipation of the … in mice/rats, when ghrelin antagonism reduced expression of …

… peptide-2 as an antagonist of GHSR that is released during calorie excess [34,35]. The …
Despite this, the mice still exhibited the same food intake and body weight changes as …

… food intake in rats [47]. … Here, we report on the in vitro and preclinical in vivo suitability of
selected NODAGA-Ghrelin receptor inverse agonists as radiotracers. Rats and mice were used …