Peripheral vascular disease: preclinical models and emerging therapeutic targeting of the vascular endothelial growth factor ligand-receptor system
… Vascular Endothelial Growth Factor-A (VEGF-A) is … disease (PAD) [Citation19], this review
focuses on the recent advances in our understanding of the ‘anti-angiogenic’ VEGF-A isoforms …
focuses on the recent advances in our understanding of the ‘anti-angiogenic’ VEGF-A isoforms …
Pro-and anti-fibrotic effects of vascular endothelial growth factor in chronic kidney diseases
C Miao, X Zhu, X Wei, M Long, L Jiang, C Li, D Jin… - Renal failure, 2022 - Taylor & Francis
… between proangiogenic and anti-angiogenic factors [Citation9]… factors such as vascular
endothelial growth factor (VEGF) and … There are three common isoforms of NOS: neuronal nitric …
endothelial growth factor (VEGF) and … There are three common isoforms of NOS: neuronal nitric …
[HTML][HTML] VEGFA Isoforms as Pro-Angiogenic Therapeutics for Cerebrovascular Diseases
AL White, GJ Bix - Biomolecules, 2023 - mdpi.com
… Currently, there are two studies showing that VEGFAx has anti-angiogenic [77] or pro-…
pro-angiogenic vascular endothelial growth factor A (VEGFA) therapy to treat patients with different …
pro-angiogenic vascular endothelial growth factor A (VEGFA) therapy to treat patients with different …
Vascular toxicity associated with anti-angiogenic drugs
KB Neves, AC Montezano, NN Lang… - Clinical Science, 2020 - portlandpress.com
… antibody (mAb), anti-vascular endothelial growth factor-A (VEGF-A), … in renal failure, arthritis,
psoriasis and coronary disease [69–72]. … VEGF induces NFATc1, one of the NFAT isoforms, …
psoriasis and coronary disease [69–72]. … VEGF induces NFATc1, one of the NFAT isoforms, …
Biology and therapeutic targeting of vascular endothelial growth factor A
L Pérez-Gutiérrez, N Ferrara - Nature Reviews Molecular Cell Biology, 2023 - nature.com
… Although the VEGF isoforms are known for their pro-angiogenic effects, inhibitory isoforms
… In 2014, a novel anti-angiogenic VEGF isoform was described, VEGFAx, with a 22-amino …
… In 2014, a novel anti-angiogenic VEGF isoform was described, VEGFAx, with a 22-amino …
[HTML][HTML] Vascular endothelial growth factor-A promoter polymorphisms, circulating VEGF-A and survival in acute coronary syndromes
BR Palmer, MA Paterson, CM Frampton, AP Pilbrow… - PLoS …, 2021 - journals.plos.org
… The well characterized heparin-binding isoform, VEGF165, is … Anti-VEGF treatment as
anti-angiogenic therapy in cancer is … Patients with serious co-morbidity (eg end-stage renal failure, …
anti-angiogenic therapy in cancer is … Patients with serious co-morbidity (eg end-stage renal failure, …
[HTML][HTML] Structural basis for vascular endothelial growth factor receptor activation and implications for disease therapy
F Shaik, GA Cuthbert, S Homer-Vanniasinkam… - Biomolecules, 2020 - mdpi.com
… promise, we examine the structural basis for anti-angiogenic therapy using small-molecule …
Thus, VEGF-E isoforms have the potential to be candidates for selectively targeting VEGFR2…
Thus, VEGF-E isoforms have the potential to be candidates for selectively targeting VEGFR2…
Antivascular endothelial growth factor‐A therapy: a novel personalized treatment approach for psoriasis
A Luengas‐Martinez, R Paus… - British Journal of …, 2022 - academic.oup.com
… Vascular endothelial growth factor‐A (VEGF‐A) mediates angiogenesis and is upregulated
in the plaques and plasma of patients with … have significant anti‐angiogenic properties and …
in the plaques and plasma of patients with … have significant anti‐angiogenic properties and …
[HTML][HTML] Vascular endothelial growth factor, a key modulator of the anti-tumor immune response
M Geindreau, F Ghiringhelli, M Bruchard - International Journal of …, 2021 - mdpi.com
… anti-angiogenic antibody approved for the treatment of colorectal cancer (CRC), and then
approved in various diseases such … directed towards all VEGF-A isoforms [75]. This antibody is …
approved in various diseases such … directed towards all VEGF-A isoforms [75]. This antibody is …
Study of endothelial vascular growth factor, markers of inflammation and vascular stiffness in chronic kidney disease
IT Murkamilov, KA Aitbaev, VV Fomin… - Clinical …, 2020 - modernonco.orscience.ru
… Assessment of the levels of vascular endothelial growth factor, … vascular stiffness indices in
chronic kidney disease. Material and methods. 261 patient with chronic kidney disease (CKD) …
chronic kidney disease. Material and methods. 261 patient with chronic kidney disease (CKD) …