Regulation of long non-coding RNAs by plant secondary metabolites: a novel anticancer therapeutic approach

MR Kalhori, H Khodayari, S Khodayari, M Vesovic… - Cancers, 2021 - mdpi.com
… glycolysis and glucose metabolism via modulation of glucose … [136] investigated the effect of
DIM on colon cancer cells. … involves regulation of cellular signal transduction pathways, such …

[HTML][HTML] … , 3'-Diindolylmethane and its derivatives: nature-inspired strategies tackling drug resistant tumors by regulation of signal transduction, transcription factors and …

B Biersack - Cancer Drug Resistance, 2020 - ncbi.nlm.nih.gov
… These natural compounds are also effective modulators of … of the effects of DIM on miRNA
expression in various tumor … with distinct activity against SW480 colon cancer cells. But in …

[HTML][HTML] Cardamonin attenuates experimental colitis and associated colorectal cancer

S James, JS Aparna, A Babu, AM Paul… - Biomolecules, 2021 - mdpi.com
… Cardamonin is a naturally occurring chalcone, majorly from the Zingiberaceae family, …
through microRNA modulation, cardamonin exerts its anti-inflammatory and anti-cancer effects

Anti-cancer effects of dietary polyphenols via ROS-mediated pathway with their modulation of microRNAs

Y Yoshioka, T Ohishi, Y Nakamura, R Fukutomi… - Molecules, 2022 - mdpi.com
… These polyphenols can also influence microRNA (miR) expression. In general, they can …
increased the expression of miR-200c and decreased the viability of colorectal cancer cells. …

Targeting cancer stem cells and signalling pathways through phytochemicals: A promising approach against colorectal cancer

W Liao, L Zhang, X Chen, J Xiang, Q Zheng, N Chen… - Phytomedicine, 2023 - Elsevier
… ), the Janus kinase-signal transducer and activator of … focus on natural plant compounds
targeting colorectal CSCs. … their efficient anti-cancer activity, abundant natural sources, …

Advancements of compounds targeting Wnt and Notch signalling pathways in the treatment of inflammatory bowel disease and colon cancer

Z Pu, F Yang, L Wang, Y Diao, D Chen - Journal of Drug Targeting, 2021 - Taylor & Francis
treatment of IBD and colon cancer. The compositions and biological effects of Wnt and Notch
modulators … Recent studies have demonstrated its anti-cancer properties. In DLD-1 and HT-…

[HTML][HTML] The role of bioactive compounds in natural products extracted from plants in cancer treatment and their mechanisms related to anticancer effects

M Yuan, G Zhang, W Bai, X Han, C Li… - … Medicine and Cellular …, 2022 - hindawi.com
… the compounds they contain with respect to their anticancer … In HCT116 human colon cancer
cells, butyrate can cause cell … in prevention of cancer via modulation of molecular pathways,…

Participation of MicroRNAs in the Treatment of Cancer with Phytochemicals

SW Son, HY Lee, S Moeng, HJ Kuh, SY Choi, JK Park - Molecules, 2020 - mdpi.com
… members via transcription factors, such as signal transduceranti-cancer effects with cisplatin
in colorectal cancer cells [236]… exert their anti-cancer effects through modulating miR-34 …

Traditional Chinese medicines as effective reversals of epithelial-mesenchymal transition induced-metastasis of colorectal cancer: molecular targets and mechanisms

H Ge, C Xu, H Chen, L Liu, L Zhang, C Wu… - Frontiers in …, 2022 - frontiersin.org
… mediated by multiple key signal transduction pathways containing … as an alternative anti-cancer
agent for cancers treatment in China … tumor cells EMT through effective modulation of the …

The anticancer effects of flavonoids through miRNAs modulations in triple-negative breast cancer

GM Adinew, E Taka, P Mendonca, SS Messeha… - Nutrients, 2021 - mdpi.com
… and treatment of TNBC through modulation of signaling … antiproliferative activity through
inhibiting signal transduction … ’ efficacy and safety as anti-cancer agents. Flavonoids are …