Ecology and evolution of antibiotic persistence
L Verstraete, B Van den Bergh, N Verstraeten… - Trends in …, 2022 - cell.com
… can also survive antibiotic attack by adopting a tolerant phenotype. In the case of persistence,
only a small fraction within an isogenic population switches to this antibiotic-tolerant state. …
only a small fraction within an isogenic population switches to this antibiotic-tolerant state. …
Antibiotic tolerance
LF Westblade, J Errington, T Dörr - PLoS pathogens, 2020 - journals.plos.org
… The same may apply to the recently described S-cells [24], which again may be … Highly
tolerant Escherichia coli cells that persist in the presence of the β-lactam ampicillin (“…
tolerant Escherichia coli cells that persist in the presence of the β-lactam ampicillin (“…
Antibiotic tolerance and persistence have distinct fitness trade-offs
… in the population, antibiotic persistence and tolerance have distinct fitness trade-offs. Our data
show that antibiotic persistence is a … cells are all kept in the same recalcitrant state. Even if …
show that antibiotic persistence is a … cells are all kept in the same recalcitrant state. Even if …
Evolution of bacterial tolerance under antibiotic treatment and its implications on the development of resistance
JE Sulaiman, H Lam - Frontiers in microbiology, 2021 - frontiersin.org
… tolerance detection, as the tolerant population may readily be killed with another antibiotic,
whereas continued treatment with the same … that increase tolerance or persistence fraction …
whereas continued treatment with the same … that increase tolerance or persistence fraction …
Antibiotic resistance and persistence—Implications for human health and treatment perspectives
… We describe the relationship between antibiotic persistence … bacterial persistence and
tolerance with the evolution of antibiotic … of antibiotics, which are fatal to other strains of the same …
tolerance with the evolution of antibiotic … of antibiotics, which are fatal to other strains of the same …
When antibiotics fail: a clinical and microbiological perspective on antibiotic tolerance and persistence of Staphylococcus aureus
… a small fraction of a population (named persisters) exhibit a tolerant … is not clear, we will
use the term ‘increased antibiotic survival’ 19 , 20 to encompass both tolerance and persistence. …
use the term ‘increased antibiotic survival’ 19 , 20 to encompass both tolerance and persistence. …
Evolutionary causes and consequences of bacterial antibiotic persistence
… We review how some aspects of antibiotic persistence have been directly … antibiotic (this
means that persistence and tolerance are the same if 100% of the population is persistent…
means that persistence and tolerance are the same if 100% of the population is persistent…
Tolerance and Persistence of Pseudomonas aeruginosa in Biofilms Exposed to Antibiotics: Molecular Mechanisms, Antibiotic Strategies and Therapeutic …
A Soares, K Alexandre, M Etienne - Frontiers in microbiology, 2020 - frontiersin.org
… cells, so that non-antibiotic alternative strategies are currently under development. … in antibiotic
tolerance and persistence in P. aeruginosa biofilm infections. A review of the antimicrobial …
tolerance and persistence in P. aeruginosa biofilm infections. A review of the antimicrobial …
Link between antibiotic persistence and antibiotic resistance in bacterial pathogens
W Eisenreich, T Rudel, J Heesemann… - Frontiers in cellular and …, 2022 - frontiersin.org
… Figure 1 Formation of the antibiotic-tolerant persistence state (according to our hypothesis).
(… that bacteriostatic antibiotics, recognizing the same primary targets as BCAs, do not trigger …
(… that bacteriostatic antibiotics, recognizing the same primary targets as BCAs, do not trigger …
Phenotypic heterogeneity in persisters: a novel 'hunker'theory of persistence
J Urbaniec, Y Xu, Y Hu… - FEMS microbiology …, 2022 - academic.oup.com
… as tolerance or dormancy. In this review we focus on ‘antibiotic persistence’ which we broadly
define as a … important aspect of persistence: it is not the same for all antibiotics. Although …
define as a … important aspect of persistence: it is not the same for all antibiotics. Although …