Mechanisms of action and limitations of monoclonal antibodies and single chain fragment variable (scFv) in the treatment of cancer
C Rodríguez-Nava, C Ortuño-Pineda, B Illades-Aguiar… - Biomedicines, 2023 - mdpi.com
… Based on the current successful antibodies and therapeutic … Despite these potential advantages
over IgG complete, the … antibody fragments with conventional mAbs, scFvs reached the …
over IgG complete, the … antibody fragments with conventional mAbs, scFvs reached the …
Antibody-mediated drug delivery
FB Arslan, K Ozturk, S Calis - International Journal of Pharmaceutics, 2021 - Elsevier
… Antibody fragments may overcome some of the drawbacks of … We next briefly explain how
antibody fragments are obtained … have clinical potential in both imaging and cancer therapy. …
antibody fragments are obtained … have clinical potential in both imaging and cancer therapy. …
Antibody and antibody fragments for cancer immunotherapy
W Chen, Y Yuan, X Jiang - Journal of controlled release, 2020 - Elsevier
… and antibodies against it have potentials in anticancer therapy. … TJ011133 developed by
I-Mab Biopharma was designed to … The specific advantages of sdAds made them suitable to …
I-Mab Biopharma was designed to … The specific advantages of sdAds made them suitable to …
An update on antiviral antibody-based biopharmaceuticals
S Ahangarzadeh, Z Payandeh, R Arezumand… - International …, 2020 - Elsevier
… reduce their limitations. These strategies contain engineered … an update on therapeutic and
diagnostic potential of mAbs for … antiviral biopharmaceuticals based on antibody fragments. …
diagnostic potential of mAbs for … antiviral biopharmaceuticals based on antibody fragments. …
Monoclonal antibody based radiopharmaceuticals for imaging and therapy
M Lin, V Paolillo, DB Le, H Macapinlac… - … Problems in Cancer, 2021 - Elsevier
… Biopharmaceuticals have gained tremendous attention in the … that antibody fragments could
be better tolerated by patients … , dosimetry and tumor targeting potential in patients with HER2…
be better tolerated by patients … , dosimetry and tumor targeting potential in patients with HER2…
Emerging new therapeutic antibody derivatives for cancer treatment
S Jin, Y Sun, X Liang, X Gu, J Ning, Y Xu… - … and Targeted Therapy, 2022 - nature.com
… therapeutic antibodies, such as antibody fragments, bispecific … Recent advantages in antibody
engineering have facilitated … a significant role in the therapeutic potential of ADCs. Usually, …
engineering have facilitated … a significant role in the therapeutic potential of ADCs. Usually, …
[PDF][PDF] Antibody Therapy: Past, Present and Future
D Moitra, PA Miraclin, N Gul, P Sen - Austin Biochem, 2021 - researchgate.net
… Minimized antibodies have several advantages like rapid … alternative is therapeutics with
antibody fragments which has … , Biopharmaceuticals refer to the drugs based on therapeutic …
antibody fragments which has … , Biopharmaceuticals refer to the drugs based on therapeutic …
Monoclonal antibodies: A prospective and retrospective view
J Sivaccumar, A Sandomenico… - Current Medicinal …, 2021 - ingentaconnect.com
… antibody fragments, … biopharmaceutical industry, challenges still persist regarding the
susceptibility of the protein to uncontrolled post-translational modifications, production limitations, …
susceptibility of the protein to uncontrolled post-translational modifications, production limitations, …
Development of therapeutic antibodies for the treatment of diseases
… To overcome problems of decreased immunogenic potential … or antibody fragments, such as
single chain fragment variable (… ever recorded for a biopharmaceutical product, nearly $19.9 …
single chain fragment variable (… ever recorded for a biopharmaceutical product, nearly $19.9 …
[HTML][HTML] Antibody-based drug delivery systems for cancer therapy: Mechanisms, challenges, and prospects
… Some antibody fragments are also rapidly metabolized in the … Further, we summarize the
problems associated with the … and ADCs have become the favorites of biopharmaceutical …
problems associated with the … and ADCs have become the favorites of biopharmaceutical …