Research progress of matrine's anticancer activity and its molecular mechanism

F Chen, Y Pan, J Xu, B Liu, H Song - Journal of Ethnopharmacology, 2022 - Elsevier
… This article summarizes current advances in research on the anticancer properties of MT
and its … Also, the anticancer efficacy of MT and its derivatives may be improved through a …

Research progress of natural Matrine compounds and synthetic Matrine derivatives

J Li, S Wei, D Marabada, Z Wang, Q Huang - Molecules, 2023 - mdpi.com
… by modifying its structure. In this review article, the research progress of matrine derivatives
… The study of the anti-tumor activity of matrine has become one of the research hotspots in …

Research advances on matrine

XY Sun, LY Jia, Z Rong, X Zhou, LQ Cao, AH Li… - Frontiers in …, 2022 - frontiersin.org
… Acid or its derivatives, and Matric Acid can be dehydrated and condensed to yield Matrine. …
The molecular conformation of Matrine also affected the anti-tumor activity and Matrine with …

Research advances on anti-cancer natural products

M Guo, J Jin, D Zhao, Z Rong, LQ Cao, AH Li… - Frontiers in …, 2022 - frontiersin.org
… The combination of Vincristine or its derivatives with other drugs showed favorable anti-tumor
activities… (118) obtained two types of Matrine derivatives by esterification to 13-hydroxyethyl …

Matrine: a promising natural product with various pharmacological activities

H Zhang, L Chen, X Sun, Q Yang, L Wan… - Frontiers in …, 2020 - frontiersin.org
… The anticancer spectrum of matrine is very wide, and it can … Matrine can alleviate the damage
of advanced glycation end … In addition, many derivatives of matrine also have antitumor, …

[HTML][HTML] Matrine family derivatives: Synthesis, reactions procedures, mechanism, and application in medicinal, agricultural, and materials chemistry

JAH Kowah, R Gao, F Li, C Guang, M Jiang… - European Journal of …, 2023 - Elsevier
… of not strong antitumor activity, but it has high … their biological activities have been studied.
Throughout this review, we highlight advances in synthesis and structural reactivity of matrine-…

Matrine: A review of its pharmacology, pharmacokinetics, toxicity, clinical application and preparation researches

X Li, Z Tang, L Wen, C Jiang, Q Feng - Journal of Ethnopharmacology, 2021 - Elsevier
… Currently, the basic researches concerning the antitumor effects of matrine-type … progress
of matrine, which does not neglect or weaken the therapeutic potential of other matrine-type …

Matrine exerts pharmacological effects through multiple signaling pathways: a comprehensive review

Y Lin, F He, L Wu, Y Xu, Q Du - Drug Design, Development and …, 2022 - Taylor & Francis
anti-tumor effects of matrine. Zhang et al Citation28 proved that … ) with matrine and then
exposed them to advanced glycation … of matrine alkaloids to develop derivative compounds with …

Natural Marine Anticancer compounds and their derivatives used in Clinical Trials

A Singla, V Singh, K Kumari, S Pathak… - Asian Journal of …, 2023 - indianjournals.com
… Despite enormous progress in anticancer drug discovery, there is a constant demand for
novel therapeutic agents due to resistance to existing chemotherapeutic drugs and …

Anti-cancer potential of sophoridine and its derivatives: Recent progress and future perspectives

H ur Rashid, S Rasool, Y Ali, K Khan… - Bioorganic Chemistry, 2020 - Elsevier
antitumor agent in 2005. This review covers the antitumor activities of sophoridine and its
derivatives… The efficacy of sophoridine analogs is expressed with respect to their half-maximal …