[HTML][HTML] Current antimycotics, new prospects, and future approaches to antifungal therapy

G Wall, JL Lopez-Ribot - Antibiotics, 2020 - mdpi.com
… can be exploited for antifungal drug development. This has also resulted in a very restricted
number of antifungal drugs that are clinically available for the treatment of invasive fungal …

[HTML][HTML] Advances in antifungal development: Discovery of new drugs and drug repurposing

JH Kim, LW Cheng, KM Land - Pharmaceuticals, 2022 - mdpi.com
… In summary, the research articles and reviews presented in this Special Issue provide … insight
for the development of new antifungal drugs or intervention strategies. Identification of new, …

[HTML][HTML] Avenues for antifungal drug discovery and development: where to now?

S Vassilopoulos, E Mylonakis - Expert Opinion on Drug Discovery, 2022 - Taylor & Francis
… In addition to studies that evaluate new antifungal agents as single agents, clinical trials
assess drug candidates as part of treatment along with the current standard of care. For example…

[HTML][HTML] Current insights on antifungal therapy: Novel nanotechnology approaches for drug delivery systems and new drugs from natural sources

F Sousa, D Ferreira, S Reis, P Costa - Pharmaceuticals, 2020 - mdpi.com
… It is important to add that resistance is a cross-cutting issue to all of the currently available
classes of antifungal agents, therefore overcoming antifungal resistance can be considered as …

Novel avenues for identification of new antifungal drugs and current challenges

J Jampilek - Expert Opinion on Drug Discovery, 2022 - Taylor & Francis
… of new antifungal drugs, provides an overview of the most important molecules in terms of
basic (laboratory) research and compounds currently in clinical trials, and focuses on drug

[HTML][HTML] Sources of antifungal drugs

G Vanreppelen, J Wuyts, P Van Dijck, P Vandecruys - Journal of Fungi, 2023 - mdpi.com
… the currently used drug classes. (1) The polyenes are the oldest antifungal drug class in
clinical use today and hallmarked a major clinical advancement in mycosis treatment. Although …

The antifungal pipeline: the need is established. Are there new compounds?

D Li, X She, R Calderone - FEMS yeast research, 2020 - academic.oup.com
… Our review summarizes and compares the temporal development (eras) of antifungal drug
New ideas and approaches were designed for bidirectional studies of the biochemistry of …

Recent progress in research on mitochondrion-targeted antifungal drugs: a review

Y Qin, J Wang, Q Lv, B Han - Antimicrobial Agents and …, 2023 - Am Soc Microbiol
drug targets, owing to their important roles in fungal viability and pathogenesis. In this review,
we discuss novel antifungal drugs … for investigating selective antifungal targets. Finally, we …

Antifungal therapy: Novel drug delivery strategies driven by new targets

S Wu, R Song, T Liu, C Li - Advanced Drug Delivery Reviews, 2023 - Elsevier
… for drug development purposes, the exploration of potential targets for novel antifungal
drug … In this review, we provide an overview of recent advancements in new antifungal drug

[HTML][HTML] Antifungal drugs

J Houšť, J Spížek, V Havlíček - Metabolites, 2020 - mdpi.com
… Currently, four antifungal drug classes are used by clinicians and veterinarians for systemic
… The research in antifungal drug development focuses on both old and new fungal targets. In …