A guide to antigen processing and presentation

N Pishesha, TJ Harmand, HL Ploegh - Nature Reviews Immunology, 2022 - nature.com
… encoded by the major histocompatibility complex (MHC) to … are important for antigen
presentation via MHC-I molecules, … MHC-I molecules or MHC-Ib molecules. These include HLA-E, …

Evolution and molecular interactions of major histocompatibility complex (MHC)-G,-E and-F genes

A Arnaiz-Villena, F Suarez-Trujillo, I Juarez… - Cellular and Molecular …, 2022 - Springer
… Recently, it is found that Qa-1b(MHC-Qa non-classical class I gene in … class I HLA molecules
(HLA-E, -F, and -G) are more restricted regarding tissue localization, antigen presentation

[HTML][HTML] Variations in MHC class I antigen presentation and immunopeptidome selection pathways

AJ Zaitouna, A Kaur, M Raghavan - F1000Research, 2020 - ncbi.nlm.nih.gov
Major histocompatibility class I (MHC-I) proteins mediate … MHC-I molecules, few such HLA-I
allotype-specific antibodies exist, … 1B). The additional incorporation of the calreticulin–ERp57 …

[PDF][PDF] Pleiotropic consequences of metabolic stress for the major histocompatibility complex class II molecule antigen processing and presentation machinery

CC Clement, PP Nanaware, T Yamazaki, MP Negroni… - Immunity, 2021 - cell.com
… alteration in antigen presentation to T cells, we analyzed the immune response to two …
presentation on IAb molecules from Ob/Ob versus control C57BL/6 mice. We also analyzed the IAb …

MHC class II presentation in autoimmunity

IA Ishina, MY Zakharova, IN Kurbatskaia, AE Mamedov… - Cells, 2023 - mdpi.com
Antigen presentation by major histocompatibility complex class II (MHC-II) molecules is …
Tregs binding Padi4 peptide in the complex with IA b [162]. The crystal structures of trimolecular …

Revisiting nonclassical HLA II functions in antigen presentation: peptide editing and its modulation

M Álvaro‐Benito, C Freund - HLA, 2020 - Wiley Online Library
… The nonclassical major histocompatibility complex of class II molecules (ncMHCII) HLA-DM
(… immune response shifts from IA d presentation in the wild-type to IE d presentation in the KO …

Cancer immune evasion through loss of MHC class I antigen presentation

K Dhatchinamoorthy, JD Colbert, KL Rock - Frontiers in immunology, 2021 - frontiersin.org
Major histocompatibility class I (MHC I) molecules bind … “non-classical” MHC class Ib
molecules, HLA-E and HLA-G (26–… of antigen presentation by “classical” MHC class Ia molecules, …

Antigen presentation by MHC-E: a putative target for vaccination?

L Voogd, P Ruibal, THM Ottenhoff, SA Joosten - Trends in immunology, 2022 - cell.com
presentation in more detail. We hypothesize that the transporter associated with antigen
presentation … The human major histocompatibility complex class Ib molecule HLA-E binds signal …

Cross-presentation of exogenous antigens on MHC I molecules

JD Colbert, FM Cruz, KL Rock - Current opinion in immunology, 2020 - Elsevier
… is one that is more analogous to the MHC class II antigen presentation pathway (Figure 1d).
In the vacuolar pathway, internalized antigens are cleaved into peptides by proteases, such …

Type II alveolar cell MHCII improves respiratory viral disease outcomes while exhibiting limited antigen presentation

SA Toulmin, C Bhadiadra, AJ Paris, JH Lin… - Nature …, 2021 - nature.com
… also express major histocompatibility complex class II (MHCII) molecules, but how … type IA
b locus (SPC-Cre-ERT2 +/− only; aka “SPC Cre ”), as well as those with homozygous floxed IA