Antimicrobial peptides as therapeutic agents: Opportunities and challenges

M Mahlapuu, C Björn, J Ekblom - Critical reviews in biotechnology, 2020 - Taylor & Francis
… into bringing new and non-conventional anti-infective drugs to the market. The antimicrobial
peptides (AMPs), also known as host defense peptides, have recently captured attention as …

[HTML][HTML] Focus: antimicrobial resistance: antimicrobial peptides therapy: an emerging alternative for treating drug-resistant bacteria

IE Mba, EI Nweze - The Yale journal of biology and medicine, 2022 - ncbi.nlm.nih.gov
… Thus, the misuse of antibiotics, which has increased resistance, has necessitated the search
for alternative therapeutic agents for combating resistant pathogens. Antimicrobial peptides (…

Antimicrobial Peptides towards Clinical Application—A Long History to Be Concluded

L Cresti, G Cappello, A Pini - International Journal of Molecular Sciences, 2024 - mdpi.com
… new and unconventional anti-infective medications to the market. Antimicrobial peptides (AMPs) …
The keywords used to search the PubMed database were “antimicrobial peptides” OR “…

The revitalization of antimicrobial peptides in the resistance era

Y Liu, J Shi, Z Tong, Y Jia, B Yang, Z Wang - Pharmacological Research, 2021 - Elsevier
peptides sequence was screened. Finally, several novel lead peptides with potent antimicrobial
… Such breakthrough expands our understanding of antimicrobial peptide chemistry and …

Antimicrobial Peptides Demonstrate Activity against Resistant Bacterial Pathogens

M Garvey - Infectious Disease Reports, 2023 - mdpi.com
Antimicrobial peptides (AMPs) are peptide sequences produced by bacteria, archaea, …
of innate immunity to infectious agents [1] as listed in the Antimicrobial Peptide Database (APD). …

Challenges and advances in antimicrobial peptide development

KBS de Oliveira, ML Leite, VA Cunha, NB da Cunha… - Drug Discovery …, 2023 - Elsevier
… of the inappropriate use of antimicrobials. In this scenario, antimicrobial peptides (AMPs)
have … molecules for the development of unusual antimicrobial drugs. We also describe current …

Antimicrobial peptides as effective agents against drug-resistant pathogens

P Tiwari, Y Srivastava, V Kumar - Antimicrobial Resistance: Underlying …, 2022 - Springer
… The antimicrobial peptides (AMPs) highlighted prospects as alternatives to conventional …
novel anti-infective agents displaying multiple mode of action, is needed. Antimicrobial peptides

Therapeutic potential of antimicrobial peptides in polymicrobial biofilm-associated infections

G Batoni, G Maisetta, S Esin - International Journal of Molecular Sciences, 2021 - mdpi.com
… The proline-rich antibacterial peptide A3-APO is a striking example of this. The peptide was
tested … in destroying pre-existing biofilms, and as carriers for other anti-infective agents for a …

Anti-infective antibody-derived peptides active against endogenous and exogenous fungi

T Ciociola, L Giovati, S Conti, W Magliani - Microorganisms, 2021 - mdpi.com
… models, lead to KP being proposed as a lead compound for a new class of antimicrobial
peptides, which can be easily synthesized or even expressed and produced in plants [52]. …

Effects of Antimicrobial Peptides on Bacteria and Viruses

TD Tavares, MO Teixeira, MA Teixeira… - Microbial …, 2023 - taylorfrancis.com
Antimicrobial peptides as anti-infective agents in pre-post-antibiotic era? International
Journal of Molecular Sciences, 20(22): 5713. Ruzsics, Z., Hoffmann, K., Riedl, A., Krawczyk, A., …