Sulforaphane ameliorates ethanol plus carbon tetrachloride-induced liver fibrosis in mice through the Nrf2-mediated antioxidant response and acetaldehyde …

K Ishida, K Kaji, S Sato, H Ogawa, H Takagi… - The Journal of nutritional …, 2021 - Elsevier
… to transforming … the enzymatic activity of a mitochondrial aldehyde dehydrogenase (ALDH),
ALDH2, which predominantly metabolizes acetaldehyde to nontoxic acetate in hepatocytes […

… C and E as the multi-antioxidants on the methylmercury intoxicated mice based on mercury bioaccumulation, antioxidant enzyme activity, lipid peroxidation and …

M Moniruzzaman, S Lee, Y Park, T Min, SC Bai - Chemosphere, 2021 - Elsevier
… substances in mice fed the mercury containing diets. Cytochrome c … enzyme activities showed
no significant differences as the mercury level increases in liver and kidney tissues of mice. …

Ethanol metabolism in the liver, the induction of oxidant stress, and the antioxidant defense system

ML Contreras-Zentella, D Villalobos-García… - Antioxidants, 2022 - mdpi.com
… may mean that the activity of MEOS is not changed by the … in liver cells has been shown to
prevent alcohol-induced liver … of cellular antioxidants [126], such as the enzymatic activities

Copper induces oxidative stress and apoptosis in the mouse liver

H Liu, H Guo, Z Jian, H Cui, J Fang… - … and cellular …, 2020 - Wiley Online Library
… for various metabolic processes and enzyme activities [2], … , the activities of GR and GST
were not significantly changed … of Cu on the activities of antioxidant enzymes and contents of …

[HTML][HTML] … plantarum KFY02 enhances the prevention of CCl4-induced liver injury by transforming geniposide into genipin to increase the antioxidant capacity of mice

Y Pan, H Wang, F Tan, R Yi, W Li, X Long, J Mu… - Journal of Functional …, 2020 - Elsevier
… 3 is an H&E stained section of the mouse liver. Normally, the liver cells are intact and
arranged in a cord-like pattern around the central vein, without infiltration of inflammatory …

Oxidative stress, genomic integrity, and liver diseases

N Sadasivam, YJ Kim, K Radhakrishnan, DK Kim - Molecules, 2022 - mdpi.com
… in reduced antioxidant levels and antioxidant enzyme activity [49]. … CYP2E1-associated
oxidative liver injury in liver cells can … Biliverdin is converted into bilirubin by an enzyme called …

[HTML][HTML] Nanocarrier-mediated antioxidant delivery for liver diseases

S Li, H Li, X Xu, PE Saw, L Zhang - Theranostics, 2020 - ncbi.nlm.nih.gov
… When HBV/HCV infects normal liver cells, the cells become … stress in liver cells as
inflamed immune cells generate … Activated HSC can transform into myofibroblast cells (MFCs), …

Modulation of antioxidant enzymes, SIRT1 and NF‐κB by resveratrol and nicotinamide in alcohol‐aflatoxin B1‐induced hepatocellular carcinoma

D Rawat, SK Chhonker, RA Naik… - Journal of Biochemical …, 2021 - Wiley Online Library
… The enzyme activity was expressed as μmol NADPH oxidized… was preceded by altered
cellular morphology of liver cells. Our results … in transformed cells due to malfunctioned metabolic …

Changes in glutathione content in liver diseases: an update

M Vairetti, LG Di Pasqua, M Cagna, P Richelmi… - Antioxidants, 2021 - mdpi.com
… react with electrophilic species transforming them into more … in the redox status greatly affect
enzymatic activity and, as a … and non-parenchymal liver cells, has been observed, as well as …

Antioxidant activities and mechanisms of polysaccharides

S Mu, W Yang, G Huang - Chemical Biology & Drug Design, 2021 - Wiley Online Library
antioxidant enzyme activity through Nrf2/ARE pathway Human antioxidant system can be
divided into enzyme antioxidant … -reduction of antioxidant enzymes to transform the oxides into …