… Apigenin inhibits the copper-mediated β-amyloid … followed by MAPK signal inactivation in
an AD cell model [32]. The … of attenuation of acetylcholinesterase levels and attenuation of …

… and cellular events such as impaired mitochondrial function, … Apigenin attenuates
coppermediated β-amyloid … and MAPK signal inactivation in an AD cell model. Brain Res 2013; …

… and/or cellular damage by altering the mitochondrial oxidative … Furthermore, apigenin
attenuates microglial activation and … molecules of natural origin with antioxidant, anti-inflammatory …

… ) signaling transduction are due to β-amyloid (Aβ)-stimuli via a … to LC1405 neuroprotection
against copper-mediated Aβ toxicity. … attenuates β-amyloidinduced toxicity through anti-…

… Akt also regulates the phosphorylation and inactivation of … In AD, the activation of MAPK
is remarkedly associated with … and mitochondrial stress through activation of MAPK in the …

… a mutation in the genes of β-amyloid precursor protein (APP) or of … Apigenin attenuates
copper-mediated beta-amyloid … and MAPK signal inactivation in an AD cell model. Brain Res. …

… is characterized by the deposition of extracellular β- amyloid as the … The copper- mediated
toxicity generated in neuronal cells causes … Apigenin prevents this toxicity by balancing the …

… phytochemical substances with strong antioxidant potential [18… is involved in the cleavage
of β-amyloid protein, as well as … the cell apoptosis rate and alleviating mitochondrial …

… attenuates copper-mediated β-amyloid neurotoxicity through antioxidation, mitochondrion
protection and MAPK signal inactivation in an AD cell model. Brain Res., 1492:33-45. …

… a higher concentration of apigenin had higher antioxidant and … lowered insoluble
concentrations of β-amyloid peptide. Such … a loss of mitochondrial transmembrane potential …