Insights Into the Role of Copper in Neurodegenerative Diseases and the Therapeutic Potential of Natural Compounds

G Zhong, X Wang, J Li, Z Xie, Q Wu… - Current …, 2024 - ingentaconnect.com
Apigenin antagonized copper-mediatedneurotoxicity in APPsw cells and exerted … that
curcumin attenuated copper-induced neurotoxicity in SH-SY5Y cells by inhibiting mitochondrial

[HTML][HTML] Studies on apigenin and its biological and pharmacological activity in brain disorders

V Kumar, S Kundu - Advanced Pharmaceutical Bulletin, 2022 - ncbi.nlm.nih.gov
… -inflammatory properties by attenuating the expression of COX-… degeneration via reversal
of mitochondrial dysfunction. … in a copper-mediated β-amyloid neurotoxicity cell model of AD. …

[HTML][HTML] … medicinal plants as neuroprotective and therapeutic properties against amyloid-β-related toxicity, and glutamate-induced excitotoxicity in human neural cells

D Lobine, N Sadeer, S Jugreet… - Current …, 2021 - ncbi.nlm.nih.gov
… , parkin translocate to depolarized mitochondria via a PINK1-… able to prevent or disrupt β
amyloid aggregation and also … has the ability to attenuate oxidative stress and neurotoxicity (for …

Therapeutic applications of apigenin and its derivatives: micro and nano aspects

H Javid, S Ahmadi, E Mohamadian - Micro Nano Bio Aspects, 2023 - mnba-journal.com
Apigenin attenuates copper-mediated β-amyloid neurotoxicity through antioxidation,
mitochondrion protection and MAPK signal inactivation in an AD cell model. Brain Research. …

Flavonoids and polyphenolic compounds as potential talented agents for the treatment of Alzheimer's disease and their antioxidant activities

R Akter, MAR Chowdhury… - Current pharmaceutical …, 2021 - ingentaconnect.com
… has been effectively attenuated by Lu (20-100 μM) not only … ) prevents copper-mediated
toxicity in β-amyloid precursor … Apigenin protects HT22 murine hippocampal neuronal cells …

Pharmacological and molecular insight on the cardioprotective role of apigenin

SD Thomas, NK Jha, SK Jha, B Sadek, S Ojha - Nutrients, 2023 - mdpi.com
Apigenin attenuated brain damage and improved neuronal … I/R injury through the mitochondrial
pathway mediated by Notch1/… and improved antioxidant activity through the regulation of …

Apigenin alleviates neuroinflammation in a mouse model of Parkinson's disease

GF Yarim, F Kazak, M Yarim, M Sozmen… - International Journal …, 2022 - Taylor & Francis
Apigenin administration attenuated MPTP-induced … with copper-mediated beta-amyloid
neurotoxic action, apigenin exerts a neuroprotective effect by maintaining mitochondrial function, …

[HTML][HTML] β-amyloid formation, memory, and learning decline following long-term ovariectomy and its inhibition by systemic administration of apigenin and β-estradiol

SB Jameie, A Pirasteh, A Naseri… - Basic and Clinical …, 2021 - ncbi.nlm.nih.gov
antioxidantanti-oxidant effects of apigenin, the present study was designed to find the
combined effects of exogenous β-estradiol hormone and apigenin on the formation of β-amyloid

NEUROPROTECTIVE AND ANTICANCER BIOACTIVITY OF APIGENIN

F KAZAK - Functional Foods and Nutraceuticals: Bioactive …, 2022 - books.google.com
Apigenin attenuates coppermediated β-amyloid neurotoxicity through antioxidation,
mitochondrion protection and MAPK signal inactivation in an AD cell model. Brain Res. 2013; 1492: …

Apigenin attenuates Aluminum phosphide-induced cytotoxicity via reducing mitochondrial/Lysosomal damages and oxidative stress in rat Cardiomyocytes

A Jahedsani, S Khezri, M Ahangari, S Bakhshii… - Pesticide biochemistry …, 2020 - Elsevier
… to cardiac failure by affecting the mitochondria through inhibition of cytochrome c oxidase, …
ameliorative effect apigenin as an antioxidant agent with mitochondrial protective potential …