… both the free FXa and the clot-bound FXa. Relative to other … as a mediator of acute inflammation
in vivo. This pathway may … , the anti-inflammatory effects of rivaroxaban and apixaban …

… for direct factor Xa (FXa) inhibitors, adexanate, will allow thrombolysis in patients on apixaban
… interaction between intravenous alteplase and NOACs, especially direct FXa inhibitors. …

… , a direct factor Xa inhibitor, suppresses tissue-factor induced human platelet aggregation
and clot-bound factor Xa in vitro: … Apixaban, a direct factor Xa inhibitor, inhibits tissue-factor …

… Apixaban (Eliquis®) is an oral, direct factor Xa inhibitor that is … Apixaban inhibits both free
and clot bound factor Xa [Citation… apixaban is that it is highly serum protein bound both in vitro (…

… test results of dabigatran and factor Xa inhibitors. After baseline … rapidly inactivates free, and
clot-bound dabigatran with a high … of the direct factor Xa-inhibitors apixaban, edoxaban, and …

… and potent orally active dual thrombin and factor Xa inhibitor,‖ J. Med. Chem., vol. … , ―Apixaban,
an oral direct factor Xa inhibitor, inhibits human clot-bound factor Xa activity in vitro,‖ …

… , rivaroxaban, between young and elderly subjects ex-vivo. 36 … , rivaroxaban, apixaban and
edoxaban, have been approved … , direct factor Xa inhibitor, which inhibits clot-bound factor Xa …

… confirms that clot-bound FXIII amounts associated with plasma FXIII activity are decreased
… In vitro addition of purified human FXIII to human fibrinogen was also associated with …

… It inhibits both free and clot-bound factor Xa and … The in vivo performance profile of the
clot-based assays in real-life … screening in patients on direct factor Xa inhibitors, such as apixaban. …

… by in vitro and in vivo anticoagulant activity tests, venous … the apixaban clinical dosage,
apixaban antithrombotic activity and bleeding increased with increasing dose, and FIXa inhibitors …