The role of phospholipid transfer protein in the development of atherosclerosis
XC Jiang, Y Yu - Current atherosclerosis reports, 2021 - Springer
… PLTP deficiency reduces VLDL and LDL levels and attenuates atherosclerosis in mouse
models, … PLTP deficiency in mice attenuates VLDL secretion from the liver [14, 51], while PLTP …
models, … PLTP deficiency in mice attenuates VLDL secretion from the liver [14, 51], while PLTP …
Inducible phospholipid transfer protein deficiency ameliorates atherosclerosis
K Zhang, J Zheng, Y Chen, J Dong, Z Li, YP Chiang… - Atherosclerosis, 2021 - Elsevier
… We found that iPLTP-KO mice had significantly lower lipid … 4A and B). Based on these
measurements, we calculated the … within the secretory pathway, regulating apoB secretion [38]. …
measurements, we calculated the … within the secretory pathway, regulating apoB secretion [38]. …
Disruption of Phospholipid Transfer Protein–Mediated High-Density Lipoprotein Maturation Reduces Scavenger Receptor BI Deficiency–Driven Atherosclerosis …
…, RB Hildebrand, B Lammers… - Arteriosclerosis …, 2020 - Am Heart Assoc
… function on atherosclerosis susceptibility in SR-BI KO mice. … metabolism of apolipoprotein
B/E-containing lipoproteins. … mice is generally associated with a lower hepatic secretion of …
B/E-containing lipoproteins. … mice is generally associated with a lower hepatic secretion of …
[HTML][HTML] Free cholesterol bioavailability and atherosclerosis
… mediates cholesterol and phospholipid transfer to APOA1, … mice display atherosclerosis
in the aortic sinus and the mice … (enlarged hearts, reduced ejection fraction and contractility, …
in the aortic sinus and the mice … (enlarged hearts, reduced ejection fraction and contractility, …
Dietary phosphatidylcholine supplementation reduces atherosclerosis in Ldlr−/− male mice2
P Aldana-Hernández, J Azarcoya-Barrera… - The Journal of nutritional …, 2021 - Elsevier
… on atherosclerosis development in male Ldlr -/− mice. We … enhance atherosclerotic
plaque formation in male Ldlr -/− mice. … mice, impaired VLDL secretion was linked to reduced …
plaque formation in male Ldlr -/− mice. … mice, impaired VLDL secretion was linked to reduced …
High Free Cholesterol Bioavailability Drives the Tissue Pathologies in Scarb1−/− Mice
J Liu, BK Gillard, D Yelamanchili… - Arteriosclerosis …, 2021 - Am Heart Assoc
… mice was isolated by heparin-manganese precipitation of plasma APOB (apolipoprotein B)
… , the FC/TC ratios of male mice were lower than those of female mice. Within ovary fat, the …
… , the FC/TC ratios of male mice were lower than those of female mice. Within ovary fat, the …
… ester transport protein transgene promotes macrophage reverse cholesterol transport in C57BL/6 mice and phospholipid transfer protein gene knockout mice
N Liu, Y Si, Y Zhang, S Guo, S Qin - Journal of physiology and …, 2021 - Springer
… -loaded macrophages in CETP-tg mice. Phospholipid transfer protein (PLTP) and CETP …
that PLTP knockout (KO) significantly decreased RCT in mice with C57BL6 background [33]…
that PLTP knockout (KO) significantly decreased RCT in mice with C57BL6 background [33]…
Atherosclerosis regression and cholesterol efflux in hypertriglyceridemic mice
… reduced HDL-C due to hypertriglyceridemia resulting from LpL deficiency would affect
atherosclerosis regression, as well as CEC, in mice … also PLTP (phospholipid transfer protein) and …
atherosclerosis regression, as well as CEC, in mice … also PLTP (phospholipid transfer protein) and …
High-density lipoproteins, reverse cholesterol transport and atherogenesis
HJ Pownall, C Rosales, BK Gillard… - Nature Reviews …, 2021 - nature.com
… -I as well as increased secretion of inflammatory cytokines … mouse model of diet-induced
atherosclerosis were impressive, showing increased reverse cholesterol transport and reduced …
atherosclerosis were impressive, showing increased reverse cholesterol transport and reduced …
Liver-specific Lxr inhibition represses reverse cholesterol transport in cholesterol-fed mice
T Nishida, M Ayaori, J Arakawa, Y Suenaga, K Shiotani… - Atherosclerosis, 2024 - Elsevier
… Hepatic Sult2b1 overexpression resulted in reduced … in HDL and apolipoprotein B–containing
lipoproteins (apoB-L). A … for reduced HDL-C levels and RCT in Ad-Sult2b1-treated mice, …
lipoproteins (apoB-L). A … for reduced HDL-C levels and RCT in Ad-Sult2b1-treated mice, …