[HTML][HTML] Signaling pathways and intervention therapies in sepsis
Y Zhang, B Ning - Signal Transduction and Targeted Therapy, 2021 - nature.com
… In a tentative exploration of hospital-treated sepsis data obtained from high-income … via
suppressing myocardial and serum inflammatory cytokines, apoptosis, and pyroptosis. STING-…
suppressing myocardial and serum inflammatory cytokines, apoptosis, and pyroptosis. STING-…
[HTML][HTML] The role and mechanism of pyroptosis and potential therapeutic targets in sepsis: a review
X Zheng, W Chen, F Gong, Y Chen, E Chen - Frontiers in immunology, 2021 - frontiersin.org
… apoptosis. A growing number of studies have investigated pyroptosis and its relationship with
sepsis, including the mechanisms, role, and relevant targets of … to explore their therapeutic …
sepsis, including the mechanisms, role, and relevant targets of … to explore their therapeutic …
[HTML][HTML] Ferroptosis in sepsis: the mechanism, the role and the therapeutic potential
L Xl, Z Gy, CN - Frontiers in Immunology, 2022 - frontiersin.org
… Ferroptosis is an iron-dependent, non-apoptotic cell death … , etc., and finding potential targets
may offer new prospects for the … In conclusion, the process of exploring the mechanism of …
may offer new prospects for the … In conclusion, the process of exploring the mechanism of …
Therapeutic targets and signaling mechanisms of vitamin C activity against sepsis: a bioinformatics study
R Li, C Guo, Y Li, Z Qin, W Huang - Briefings in bioinformatics, 2021 - academic.oup.com
… Our bioinformatics analysis clearly showed that the four identified core targets might beneficially
suppress sepsis-associated epithelial cell necrosis or apoptosis in the lung, peritoneum …
suppress sepsis-associated epithelial cell necrosis or apoptosis in the lung, peritoneum …
The potential immunological mechanisms of sepsis
X Zhang, Y Zhang, S Yuan, J Zhang - Frontiers in Immunology, 2024 - frontiersin.org
… -depth exploration of the critical mechanisms underlying sepsis, … DCs could be a promising
therapeutic target for sepsis (41). … apoptosis has been demonstrated to lower sepsis mortality (…
therapeutic target for sepsis (41). … apoptosis has been demonstrated to lower sepsis mortality (…
Sepsis therapies: learning from 30 years of failure of translational research to propose new leads
… A summary of transcriptomic studies exploring subgroup responses can be found in Table 3…
to sepsis is a major cause of difficulties in the development of effective targeted therapies. By …
to sepsis is a major cause of difficulties in the development of effective targeted therapies. By …
[HTML][HTML] Immune checkpoints: novel therapeutic targets to attenuate sepsis-induced immunosuppression
MA McBride, TK Patil, JK Bohannon… - Frontiers in …, 2021 - frontiersin.org
… of sepsis pathology and identify novel biological targets for the development of new therapeutics.
… -3/7 + apoptotic T cells in a murine CLP model of sepsis, thereby implicating 2B4 as an …
… -3/7 + apoptotic T cells in a murine CLP model of sepsis, thereby implicating 2B4 as an …
[HTML][HTML] The critical roles and mechanisms of immune cell death in sepsis
Z Cheng, ST Abrams, J Toh, SS Wang, Z Wang… - Frontiers in …, 2020 - frontiersin.org
… and a potential combined therapeutic strategy for targeting sepsis. … mediate lymphocyte
apoptosis in sepsis (55). Bcl-2 is an anti-apoptosis protein and is found to be reduced in sepsis (…
apoptosis in sepsis (55). Bcl-2 is an anti-apoptosis protein and is found to be reduced in sepsis (…
[HTML][HTML] Exploring the pathophysiology of post-sepsis syndrome to identify therapeutic opportunities
EC van der Slikke, AY An, REW Hancock… - EBioMedicine, 2020 - thelancet.com
… to develop new therapeutic opportunities to improve survival rate and quality of life of sepsis
… A sepsis follow-up clinic may be useful to identify long-term health issues associated with …
… A sepsis follow-up clinic may be useful to identify long-term health issues associated with …
Classic Signaling Pathways in Alveolar Injury and Repair Involved in Sepsis‐Induced ALI/ARDS: New Research Progress and Prospect
W Li, D Li, Y Chen, H Abudou, H Wang, J Cai… - Disease …, 2022 - Wiley Online Library
… in sepsis-induced ALI/ARDS may provide new targets and … Recent studies have been
conducted to explore the effects of the … the lung damage from sepsis by reducing apoptosis [60, …
conducted to explore the effects of the … the lung damage from sepsis by reducing apoptosis [60, …