… This review outlines mechanisms of cancer-related … ” induced in the absence of apparent
pathogenic infection. … both genomic instability and direct insertional mutagenesis of diverse …

… new cancer diagnoses and cancer-related deaths worldwide. The … of somatic mutations linked
with chromosomal instability (CIN). … are exceptionally sensitive to DNA mismatching errors. …

… in this setting, an evident trend emerged where the magnitude … next-generation sequencing
of 315 cancer-related genes, … mutational burden and microsatellite instability status, as well …

… information on colon cancer related to personalized medicine. … The apparent potential
of incorporating comprehensive … tumor types more prevalent in microsatellite instability (MSI-H)/…

… A number of proposed mechanisms involving failure to repair … All in all, it is evident that
more research into the biology of … size (only three breast cancer-related samples), the group …

… in genetic alterations leading to genomic instability and … Crossover sites mature into
cytologically visible chiasmata that … associated with higher thyroid cancer-related mortality, while …

… as the fourth leading cause of cancer-related fatalities in 2020. … sequence is often accompanied
by chromosomal instability (… in CRC is becoming increasingly evident. In this regard, …

… Notably, there were obvious differences in CD93 expression … generate errors during DNA
replication, and MMR genes can … expression and other cancer-related biological functions in …

… 4 9 Cancer cells have poor genetic stability. Carcinogens cause mutations … Others are not
easily visible. Some … involved in about 80 percent of stomach cancers. One hundred years ago, …

… for about 10% of cancer-related mortality in western countries. … which can present as visible
bleeding with bowel movements … pathways involved within the genetic instability of CRC and …