[HTML][HTML] Construction of a novel LncRNA signature related to genomic instability to predict the prognosis and immune activity of patients with hepatocellular carcinoma
J Zhu, Q Huang, S Liu, X Peng, J Xue, T Feng… - Frontiers in …, 2022 - frontiersin.org
… Liver cancer is the third leading cause of cancer-related death … the protection of genome
integrity, diversification of antibody … Among them, 10 GILncRNAs with the most obvious up-…
integrity, diversification of antibody … Among them, 10 GILncRNAs with the most obvious up-…
[PDF][PDF] Understanding the role of novel cancer-related gene C1ORF112 in relation to DNA damage and repair
UOJ Edogbanya - 2023 - livrepository.liverpool.ac.uk
… , segregation, and cell replication. Model structures for C1ORF112 … Genome stability is
linked to chromosome stability and … of protection to the genome and allows for epigenetic gene …
linked to chromosome stability and … of protection to the genome and allows for epigenetic gene …
[HTML][HTML] Cytidine deaminase resolves replicative stress and protects pancreatic cancer from DNA-targeting drugs
A Lumeau, N Bery, A Frances, M Gayral, G Labrousse… - Cancer Research, 2024 - AACR
… and has been shown to protect cancer cells from deoxycytidine-… , and regulated genetic
stability during DNA replication. In … have been developed for cancer-related therapy, but they lack …
stability during DNA replication. In … have been developed for cancer-related therapy, but they lack …
From Oncogenic Replication Stress to Drug Resistance: F-Box Proteins as Signalling Hubs in Cancer
A Brunner - 2021 - search.proquest.com
… and their targets in cancer-related pathways and pinpoint … response (DDR) are visible, such
as H2AX phosphorylated on … a potent driver of replication stress and genetic instability when …
as H2AX phosphorylated on … a potent driver of replication stress and genetic instability when …
[HTML][HTML] RAP1/TERF2IP—a multifunctional player in cancer development
A Deregowska, M Wnuk - Cancers, 2021 - mdpi.com
… a critical role in maintaining chromosome stability. However, … in each round of DNA replication
in cancer cells. Some cancer … exhibited the upregulation of cancer-related proteins, such …
in cancer cells. Some cancer … exhibited the upregulation of cancer-related proteins, such …
Microsatellite instability at tetranucleotides (EMAST) in colorectal cancer: clinical relevance, mechanisms and immune markers
MM Watson - 2020 - bora.uib.no
… second-leading cause of cancer-related death and a global … Such variability is for example
evident in the GI tract, where … as RER (replication error) 88,89, and linked to a genetic locus …
evident in the GI tract, where … as RER (replication error) 88,89, and linked to a genetic locus …
[HTML][HTML] G-quadruplex stabilization via small-molecules as a potential anti-cancer strategy
A Awadasseid, X Ma, Y Wu, W Zhang - Biomedicine & Pharmacotherapy, 2021 - Elsevier
… by small-molecules in cancer-related genes with the aim to … , such as replicating DNA, gene
expression, preservation of … instability was reinforced by the human genome sequencing of …
expression, preservation of … instability was reinforced by the human genome sequencing of …
[HTML][HTML] PrimPol: a breakthrough among DNA replication enzymes and a potential new target for cancer therapy
A Díaz-Talavera, C Montero-Conde, LJ Leandro-García… - Biomolecules, 2022 - mdpi.com
… , leading to replication stress and genome instability. There … This pathway could also stabilize
and protect the replication … DNA replication, and thereby cell proliferation, becomes evident …
and protect the replication … DNA replication, and thereby cell proliferation, becomes evident …
The Genetics and Epigenetics of Centromeres in Cancer
A Saha - 2021 - deepblue.lib.umich.edu
… compartmentalization of replication and segregation is … we had previously known about
genomic instability in cancer while … the second leading cause of cancer-related death in men22. …
genomic instability in cancer while … the second leading cause of cancer-related death in men22. …
[HTML][HTML] Pseudogenes in Cancer: State of the Art
AK Nakamura-García, J Espinal-Enríquez - Cancers, 2023 - mdpi.com
… -based duplication events that replicate an entire gene locus, … strand based on its
thermodynamic stability. The guide strand … which has been linked to cancer-related malignant …
thermodynamic stability. The guide strand … which has been linked to cancer-related malignant …