Oligonucleotides and microRNAs targeting telomerase subunits in cancer therapy
A Eckburg, J Dein, J Berei, Z Schrank, N Puri - Cancers, 2020 - mdpi.com
… genomic stability in normal somatic cells and protect against … miRNAs often target genes
involved in cancer-related … During DNA replication, once the replication fork reaches the …
involved in cancer-related … During DNA replication, once the replication fork reaches the …
[HTML][HTML] The role of alternative splicing in human cancer progression
J Ouyang, Y Zhang, F Xiong, S Zhang… - American Journal of …, 2021 - ncbi.nlm.nih.gov
… the alternative splicing of cancer-related genes, according to cancer … The instability of U1
and U4 snRNPs leads to their … understood, and it is obvious that more studies pertaining to the …
and U4 snRNPs leads to their … understood, and it is obvious that more studies pertaining to the …
PBRM1, SETD2 and BAP1—the trinity of 3p in clear cell renal cell carcinoma
J Walton, K Lawson, P Prinos, A Finelli… - Nature Reviews …, 2023 - nature.com
… of crucial cancer-related pathways, including protection of genomic stability, antagonism of
… The accessibility of DNA sequences for transcription, replication and repair is achieved in …
… The accessibility of DNA sequences for transcription, replication and repair is achieved in …
Genomic instability in stem cells: the basic issues
EA Prieto González, KH Haider - Stem cells: from potential to promise, 2021 - Springer
… , and senescence resulting from replication stress, chromosomal … The apparent similarity
between hESCs and hiPSCs … iPSC exome, especially in cancer-related genes. From the total …
between hESCs and hiPSCs … iPSC exome, especially in cancer-related genes. From the total …
Altered DNA repair creates novel Alu/Alu repeat‐mediated deletions
ME Morales, T Kaul, JN Walker, C Everett… - Human …, 2021 - Wiley Online Library
… of nonallelic homology that influences genetic instability in the human … To replicate these
findings in a more stable approach, we … Other cells with typical cancer-related mismatch-repair …
findings in a more stable approach, we … Other cells with typical cancer-related mismatch-repair …
Impact of low replication stress on the replication program of cancer and non-tumor cells
L Courtot - 2020 - theses.hal.science
… lead DNA replication stress, genomic instability and cancer. In … after chemotherapy is the
major cause of cancer-related … or FA pathways are becoming evident. What determines whether …
major cause of cancer-related … or FA pathways are becoming evident. What determines whether …
Catastrophic endgames: emerging mechanisms of telomere-driven genomic instability
… Recently, it has become apparent that that the resolution of dicentric chromosomes, which
… as a t-loop. Telomeres undergo shortening from progressive end-replication losses or from …
… as a t-loop. Telomeres undergo shortening from progressive end-replication losses or from …
DNA methylation profiling of hTERT gene alongside with the telomere performance in gastric adenocarcinoma
S Vahidi, SE Norollahi, S Agah… - Journal of Gastrointestinal …, 2020 - Springer
… can impress the gene expression and genomic stability and cause … to be completely replicated
during replication, and RNA … and miRNA via silencing cancer-related genes or the control …
during replication, and RNA … and miRNA via silencing cancer-related genes or the control …
Hereditary Colorectal Cancer: State of the Art in Lynch Syndrome
A Nolano, A Medugno, S Trombetti, R Liccardo… - Cancers, 2022 - mdpi.com
… as a “sensor” for DNA replication errors caused by DNA base … high instability (MSI-H); those
with instability in a repeat are … strategies to decrease cancer-related morbidity and mortality. …
with instability in a repeat are … strategies to decrease cancer-related morbidity and mortality. …
[HTML][HTML] The regulatory function of piRNA/PIWI complex in cancer and other human diseases: The role of DNA methylation
DD Jia, H Jiang, YF Zhang, Y Zhang… - … journal of biological …, 2022 - ncbi.nlm.nih.gov
… levels of transposons and protecting genomic stability 61 . … featured with the clonal replication
of plasma cells in the bone … methylation levels in some cancer-related genes are related to …
of plasma cells in the bone … methylation levels in some cancer-related genes are related to …