[HTML][HTML] Aquaporin 5 facilitates corneal epithelial wound healing and nerve regeneration by reactivating Akt signaling pathway

Y Liu, G Di, Y Wang, D Chong, X Cao… - The American journal of …, 2021 - Elsevier
… The findings of the present study show a significant impairment in corneal wound healing
in the AQP5 −/− mice due to distinct defects in corneal epithelial cell proliferation and nerve …

Role of aquaporins in corneal healing post chemical injury

ME Bhend, D Kempuraj, NR Sinha, S Gupta… - Experimental eye …, 2023 - Elsevier
… in abnormal corneal wound healing is … enhances corneal wound healing mechanisms and
corneal homeostasis. This review aims to highlight the role of AQPs in corneal wound healing

Loss of aquaporin 5 contributes to the corneal epithelial pathogenesis via Wnt/β‐catenin pathway

Y Wang, G Di, K Zhang, Y Bai, X Cao… - The FASEB …, 2023 - Wiley Online Library
corneal transparent epithelial in Aqp5−/− corneas. We also found that pre- stimulated
Aqp5−/− primary cornealAquaporin 5 facilitates corneal epithelial wound healing and nerve …

Aquaporins in the Cornea

S Melnyk, WB Bollag - International Journal of Molecular Sciences, 2024 - mdpi.com
AQP5 in the cornea appear to involve the general maintenance of corneal structure, as well
as corneal wound healing … that AQP5 facilitates corneal epithelial wound healing and nerve …

Aquaporin 5 in the eye: expression, function, and roles in ocular diseases

K Zhang, G Di, Y Bai, A Liu, W Bian, P Chen - Experimental Eye Research, 2023 - Elsevier
AQP5 is expressed in many eye tissues and plays critical roles, such as maintaining the
transparency of the cornea and lens, promoting corneal wound healing, maintaining tear film …

[HTML][HTML] Dioleoylphosphatidylglycerol accelerates corneal epithelial wound healing

WB Bollag, LO Olala, D Xie, X Lu, H Qin… - … & visual science, 2020 - arvojournals.org
… We previously demonstrated in epidermal keratinocytes that the glycerol channel aquaporin-3
(AQP3) interacts with phospholipase D2 (PLD2) to produce the signaling phospholipid …

[HTML][HTML] Topical naltrexone increases aquaporin 5 production in the lacrimal gland and restores tear production in diabetic rats

D Diaz, JP Sassani, IS Zagon… - … Biology and Medicine, 2024 - ncbi.nlm.nih.gov
… Studies have suggested that corneal nerve … in corneal would healing [39, 40]. We have
previously shown that topical naltrexone increased corneal wound healing and increased corneal

Lycium barbarum polysaccharide promotes corneal re-epithelialization after alkaline injury

HL Wong, Y Bu, YK Chan, KC Shih - Experimental eye research, 2022 - Elsevier
… potential effect of LBP in promoting cornea wound healing after an alkali burn … AQP5
expression at day 3 after alkali burn injury with LBP pre-treatment. No significant difference in AQP5

Loss of AQP5 Contributes to the Corneal Epithelial Pathogenesis Via Wnt/β-Catenin Pathway

Y Wang, G Di, K Zhang, Y Bai, X Cao, H Zhao… - papers.ssrn.com
Corneal epithelial wound model was used to investigate the effect of AQP5 on wound healing
expressed genes were identify in the corneal epithelium of AQP5+/+ and AQP5-/- mice by …

A systematic review on cornea epithelial-stromal homeostasis

HL Wong, SHL Poon, Y Bu, ACY Lo, V Jhanji… - Ophthalmic …, 2021 - karger.com
… PDGF-BB and bFGF are involved in corneal wound healing, but their actions on ECM … Spatial
expression of aquaporin 5 in mammalian cornea and lens, and regulation of its localization …