… the function of IgM. Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) is a
… determined in this study to the VAR2CSA–CSA complex structure (PDB ID: 7JGH) 24 . Fcμ–J …

… We next measured IgG and IgM levels in the blood of mice infected with N67 or N67C, …
group of Plasmodium molecules, such as Plasmodium falciparum erythrocyte membrane protein (…

… modifies infected red blood cell architecture to promote its … and immunogenic; MSP-1-specific
IgM and IgG titres persisted … AMA-1 domain III interaction with RBC membrane protein Kx …

… falciparum protein PfEMP1(P. falciparum Erythrocyte Membrane Protein 1), expressed on the
surface of … Our structure also shows that DBL3X and DBL5ε directly interact with the Cµ4 of …

… Plasmodium falciparum Erythrocyte Membrane Protein (PfEMP1) family at their surface. The
polymorphic VAR2CSA protein … definition of the architecture of the IgM/PfEMP1 complex (107…

… This architecture of VAR2CSA is conserved in all studied P. falciparum strains. Anti-adhesion
antibodies, that appear after one or two successive pregnancies in malaria endemic …

… falciparum expresses a family of proteins, referred to as erythrocyte membrane protein 1 (PfEMP1), …
In addition to the CSA–VAR2CSA complex, we also solved the structure of CSA-free …

… The circumsporozoite protein (CSP) of Plasmodium falciparum malaria has been the
foundation for the design of transmission blocking malaria vaccines. To date, the most promising …

… from Plasmodium falciparum–specific IgM + and IgG + human … We verified the quaternary
structure of our recombinant IgM … human IgM molecules, derived from CD21 + CD27 + IgM + …

… with plasma at a final dilution of 1:100 for 1 hour, followed by a 1 hour incubation with anti-human
IgG-AP (Sigma Aldrich, 1:1500) or anti-human IgM-AP (Sigma Aldrich, 1:1500). Next, …