In Vitro Cytotoxic and Ultrastructural Effects of Selected Carboxylic Ionophores on Cardiac and Skeletal Myoblasts

D Henn - 2022 - search.proquest.com
… 51 Figure 3.6 H9c2 myoblasts in complete DMEM (a) and H9c2 myoblasts at day 8 of …
Additionally, more detailed analysis on the effect ionophores have on cell and organelle …

Characterization of the far-red fluorescent probe MitoView 633 for dynamic mitochondrial membrane potential measurement

P Ernst, S Kim, Z Yang, XM Liu, L Zhou - Frontiers in Physiology, 2023 - frontiersin.org
… 633, we conducted measurements in H9C2 cells at 37C, using … potential impact of MitoView
633 on cellular bioenergetics. … assessed the effects of MitoView 633 staining on AC16 cells. …

Imine stilbene analog ameliorate isoproterenol-induced cardiac hypertrophy and hydrogen peroxide-induced apoptosis

GK Raut, S Manchineela, M Chakrabarti… - Free Radical Biology …, 2020 - Elsevier
… performed Western blot analysis of GATA4 in ISO induced hypertrophic H9c2 cells. GATA4
… of ISO treatment in H9c2 cells caused changes in mitochondrial bioenergetics in which the …

The role of mitochondria in myocardial damage caused by energy metabolism disorders: From mechanisms to therapeutics

A Li, L Lian, X Chen, W Cai, X Fan, Y Fan, T Li… - Free Radical Biology …, 2023 - Elsevier
… Fifthly, in addition to normal drugs, we have focused on the therapeutic effect of traditional
Chinese medicine on this myocardial damage, hoping to o provide a reference for clinical …

Total Matrix Ca2+ Modulates Ca2+ Efflux via the Ca2+/H+ Exchanger in Cardiac Mitochondria

GK Natarajan, L Glait, J Mishra, DF Stowe… - Frontiers in …, 2020 - frontiersin.org
… mitochondria and permeabilized H9c2 cells. Mitochondria were … of LETM1 in permeabilized
H9c2 cells modulated Ca 2+ … by measuring RCI to assess respiration using an oxygraph (…

Diazoxide attenuates DOX-induced cardiotoxicity in cultured rat myocytes

C Guven, E Taskin, Ö Aydın, ST Kaya… - Biotechnic & …, 2024 - Taylor & Francis
assessment of MMP according to the vendor’s instructions. Briefly, control or treated …
that DOX triggered apoptotic cell death mechanisms in rat embryonic heart muscle H9c2

Mitoxantrone impairs proteasome activity and prompts early energetic and proteomic changes in HL-1 cardiomyocytes at clinically relevant concentrations

VM Costa, JP Capela, JR Sousa, RP Eleutério… - Archives of …, 2020 - Springer
… We conducted an early assessment of MTX toxicity in HL-1 cells. In earlier time points (6 …
use of caspase inhibitors did not prevent it in differentiated H9c2 cells (Reis-Mendes et al. 2017)…

[HTML][HTML] PHB2 ameliorates Doxorubicin-induced cardiomyopathy through interaction with NDUFV2 and restoration of mitochondrial complex I function

M Yang, M Abudureyimu, X Wang, Y Zhou, Y Zhang… - Redox biology, 2023 - Elsevier
… and bioenergetic capacity providing indispensable roles in the maintenance of cellular
the top enriched biological processes, while GO analysis for cellular component (CC) noted …

The role of c subunit of F1FO-ATP synthase in mitochondrial permeability transition pore activity for the treatment of reperfusion injury after myocardial infarction

G Pedriali - 2020 - sfera.unife.it
… To assess the efficacy of PP11 in inhibiting Ca2+-mediated mPTP opening, we first
measured its biological activity in HeLa cells by calcein-cobalt assay (34). mPTP opening was …

Reduced immunity regulator MAVS contributes to non-hypertrophic cardiac dysfunction by disturbing energy metabolism and mitochondrial homeostasis

Q Wang, Z Sun, S Cao, X Lin, M Wu, Y Li, J Yin… - Frontiers in …, 2022 - frontiersin.org
… (MMP), we measured the MMP level of H9C2 cells. Con-focal images and Flow cytometry
analysis of control and H9C2-/- cells both demonstrated reduced MMP levels (Figures 5G, H). …