Pathways in uremic cardiomyopathy–the intracellular orchestrator PGC-1α in cell culture and in a mouse model of uremia
TJ Bergmann - 2022 - opus.bibliothek.uni-wuerzburg.de
… Erk in urea-treated h9c2 cells. Western blot analysis of h9c2 cells that were treated with
glucose, … capacity indicates how close a cell is operating to its bioenergetic limit. After adding the …
glucose, … capacity indicates how close a cell is operating to its bioenergetic limit. After adding the …
Cardiac Troponin I Directly Binds and Inhibits Mitochondrial ATP Synthase: a Noncanonical Role in the Post-Ischemic Heart
… mitochondrial function, bioenergetics and redox balance in … To visualize cTnI localization,
we transfected H9c2 cardiac … We therefore assessed the effect of P888 treatment on the …
we transfected H9c2 cardiac … We therefore assessed the effect of P888 treatment on the …
BDNF mimetic 7, 8-dihydroxyflavone rescues rotenone-induced cytotoxicity in cardiomyocytes by ameliorating mitochondrial dysfunction
PZ Hang, FQ Ge, MR Zhang, QH Li, HQ Yu… - Free Radical Biology …, 2023 - Elsevier
… Mitochondrial dysfunction, which is characterized by bioenergetic impairment and … analysis
of phosphorylation STAT3 at Tyr705 site in the cytoplasmic and nuclear fractions of H9c2 cells…
of phosphorylation STAT3 at Tyr705 site in the cytoplasmic and nuclear fractions of H9c2 cells…
Cell-permeable succinate rescues mitochondrial respiration in cellular models of amiodarone toxicity
AM Bețiu, I Chamkha, E Gustafsson, E Meijer… - International Journal of …, 2021 - mdpi.com
… -linked (Figure 2G) OXPHOS, we assessed the effects of amiodarone and rotenone (as the
positive control for complex I-inhibition) on mitochondrial respiration and cellular ATP levels. …
positive control for complex I-inhibition) on mitochondrial respiration and cellular ATP levels. …
Carvedilol Phenocopies PGC-1α Overexpression to Alleviate Oxidative Stress, Mitochondrial Dysfunction and Prevent Doxorubicin-Induced Toxicity in Human iPSC …
N Uche, Q Dai, S Lai, K Kolander, M Thao, E Schibly… - Antioxidants, 2023 - mdpi.com
… To assess cell protection, we first incubated H9c2 cells and … before performing an assessment
of the cell viability using the … effects of carvedilol are primarily to preserve bioenergetic …
of the cell viability using the … effects of carvedilol are primarily to preserve bioenergetic …
Protective effects of β-caryophyllene on mitochondrial damage and cardiac hypertrophy pathways in isoproterenol-induced myocardial infarcted rats
A Yovas, SP Stanely, SMP Ponnian - European Journal of Pharmacology, 2023 - Elsevier
… assessed the effects of β-caryophyllene on these enzymes and Ca 2+ . The hypoxia in
tissues and surplus free radicals production by isoproterenol reduces the activities of TCA cycle …
tissues and surplus free radicals production by isoproterenol reduces the activities of TCA cycle …
Identification of small molecules inhibiting cardiomyocyte necrosis and apoptosis by autophagy induction and metabolism reprogramming
D Liu, F Peyre, YA Loissell-Baltazar, D Courilleau… - Cells, 2022 - mdpi.com
… The percentage of viable cells was evaluated by methylene blue staining [10]. After … to
measure cellular bioenergetic function. H9c2 cells were seeded at 20,000 cells per well in XFe96 …
measure cellular bioenergetic function. H9c2 cells were seeded at 20,000 cells per well in XFe96 …
MMP9 inhibition increases autophagic flux in chronic heart failure
… In this study, by assessing left … H9c2 cells was validated by Western immunoblot and in-gel
gelatin zymography techniques. We represent these cells as knockdown MMP9 +/− H9c2 …
gelatin zymography techniques. We represent these cells as knockdown MMP9 +/− H9c2 …
H2S-mediated blockage of protein acetylation and oxidative stress attenuates lipid overload-induced cardiac senescence
… The developed colour of methylene blue was quantified at … the effect of H 2 S on cardiac
cell senescence, H9C2 cells … change, we then assessed the global acetylated lysine level …
cell senescence, H9C2 cells … change, we then assessed the global acetylated lysine level …
The Role of Mitochondrial Bioenergetics in Cell Death Mechanisms in the Heart: Ferroptotic Pathways
XR Chapa-Dubocq - 2021 - search.proquest.com
… chemically induced ferroptosis in H9c2 cells. FIGURE 5.9. … assessing the role of ferroptosis
in cardiac dysfunction, we will expand our knowledge on the impact of this relatively new cell …
in cardiac dysfunction, we will expand our knowledge on the impact of this relatively new cell …