Nicotinamide mononucleotide imparts protection against Doxorubicin-induced cardiotoxicity by maintaining lysosomal acidification

N Nalin - 2020 - search.proquest.com
… DOX induced cell injury and altered the lysosomal pH of H9c2 cells, an in vitro model of
cardiomyocytes. These effects of DOX were attenuated by NMN. The protection conferred by …

Mitochondrial transplantation: A promising therapy for mitochondrial disorders

Q Jiao, L Xiang, Y Chen - International Journal of Pharmaceutics, 2024 - Elsevier
… internalization and even a bioenergetic shift from glycolysis … exogenous mitochondria into
H9c2 heart myoblast cells 24 h … , fluorescence-activated cell sorting, and mtDNA analysis, and …

Sulfur signaling pathway in cardiovascular disease

Y Song, Z Xu, Q Zhong, R Zhang, X Sun… - Frontiers in …, 2023 - frontiersin.org
… was overexpressed, these effects were blocked. The survival of H9c2 cells exposed to Η 2 Ο
… A drawback of this fluorescence technique is its limited applicability for proteomic analysis. …

Investigating the role of Osteopontin in cardiac hypertrophy

AL Asirvatham - 2022 - theses.gla.ac.uk
… Furthermore, we aimed to assess the functional role of … H9c2 and HeLa conditioned media
on H9c2 cells. Over-expression of Spp1 in H9c2 cells results in a significant increase in cell

Development of hydropersulfide donors to study their chemical biology

VS Khodade, SC Aggarwal, A Eremiev… - Antioxidants & Redox …, 2022 - liebertpub.com
… role in mitochondrial biogenesis and bioenergetics (1). … Interestingly, pretreating H9c2 cells
with this RSSH precursor for 2 … H 2 S release with the methylene blue assay, and it was found …

Peptide Vectors Carry Pyrene to Cell Organelles Allowing Real‐Time Quantification of Free Radicals in Mitochondria by Time‐Resolved Fluorescence Microscopy

MJ Wawi, A Bijoux, N Inguimbert, C Mahler… - …, 2021 - Wiley Online Library
… , are needed and assessed using cells placed under nitrogen … to exhibit significant or
irreversible bioenergetic alteration at … measurements performed on single H9c2 cells with our time-…

Developmental toxicity assessment of 4-MBC in Danio rerio embryo-larval stages

V Prakash, V Jain, SS Chauhan, R Parthasarathi… - Science of The Total …, 2022 - Elsevier
… Furthermore, immunoblot analysis confirms 4-MBC induced apoptosis in zebrafish larvae
with … toxicity of 4-MBC and the information shall be used for aquatic toxicity risk assessment. …

[HTML][HTML] Semaglutide attenuates doxorubicin-induced cardiotoxicity by ameliorating BNIP3-Mediated mitochondrial dysfunction

X Li, W Luo, Y Tang, J Wu, J Zhang, S Chen, L Zhou… - Redox Biology, 2024 - Elsevier
… The semithin sections were stained with methylene blue, while ultrathin sections were cut …
the two groups were assessed using a 2-tailed unpaired Student's t-test. Survival analysis was …

Rational design of near-infrared fluorescent probes for superoxide anion radical: enhancement of self-stability and sensitivity by self-immolative linker

K Ji, J Shan, X Wang, X Tan, J Hou, Y Liu… - Free Radical Biology and …, 2021 - Elsevier
… induced cardiotoxicity in H9c2 cells by correlating the O 2 •- generation with the cell viability.
… 5.0 eq, blue) in PBS (20 mM, pH 7.4, 30% DMSO) for 30 min and then HPLC analysis was …

Pathways for Developing an Ischemic Cardiac Targeting Nanoparticle Drug Delivery System

KR Jones - 2023 - search.proquest.com
… biomaterial for nanoparticle synthesis, engineer nanoparticles for systemic delivery, and
assess their effect in vitro using a myoblast-like cell model of ischemia-reperfusion injury. …