Epigenetics: An overview of CpG methylation, chromatin remodeling, and regulatory/noncoding RNAs
… As compared to passive demethylation, active demethylation … each of these regulates
chromatin structure: posttranslational … , remodeling complexes alter chromatin organization by …
chromatin structure: posttranslational … , remodeling complexes alter chromatin organization by …
Sequence determinants, function, and evolution of CpG islands
A Angeloni, O Bogdanovic - Biochemical Society Transactions, 2021 - portlandpress.com
… in mouse DNA fragments resulted in alterations to 5mC levels, … with the potent demethylating
agent 5-azacytidine (5-aza-C) … , 5-aza-C treatment induced global DNA demethylation and …
agent 5-azacytidine (5-aza-C) … , 5-aza-C treatment induced global DNA demethylation and …
[HTML][HTML] Understanding the interplay between CpG island-associated gene promoters and H3K4 methylation
… [5,6]). A subset of histone modifications appears to directly regulate chromatin structure by
… Much like histones, DNA can be modified in several ways, most notably by the methylation …
… Much like histones, DNA can be modified in several ways, most notably by the methylation …
Luteolin causes 5′ CpG demethylation of the promoters of TSGs and modulates the aberrant histone modifications, restoring the expression of TSGs in human …
… is linked to abnormal epigenetic alterations such as DNA … chromatin structure and reactivate
silenced genes [12,13], potentially reverting malignancy-associated epigenetic alterations in …
silenced genes [12,13], potentially reverting malignancy-associated epigenetic alterations in …
Decitabine disrupts EBV genomic epiallele DNA methylation patterns around CTCF binding sites to increase chromatin accessibility and lytic transcription in gastric …
… patterning and its association with euchromatin domains … EBV genome CTCF binding
sites sat in demethylated … usually display altered gene expression patterns and an altered …
sites sat in demethylated … usually display altered gene expression patterns and an altered …
[HTML][HTML] Local CpG density affects the trajectory and variance of age-associated DNA methylation changes
… age-associated alterations in DNA methylation at the CpG level, … of the association was also
similar when we removed CpG … TET1 which plays a role in demethylation as well as CFP1, …
similar when we removed CpG … TET1 which plays a role in demethylation as well as CFP1, …
[HTML][HTML] CpG Islands shape the epigenome landscape
… that will be epigenetically modified. … that the promoter architecture and its epigenetic
organization is DNA-… showed an open chromatin structure around the TSS (as evidenced by …
organization is DNA-… showed an open chromatin structure around the TSS (as evidenced by …
5-Hydroxymethylcytosine-mediated active demethylation is required for mammalian neuronal differentiation and function
… , transcription and chromatin organization during their … PCs results in altered transcriptional
regulation despite the … methylation, transcription, and chromatin structure, we note that there …
regulation despite the … methylation, transcription, and chromatin structure, we note that there …
The role of thymine DNA glycosylase in transcription, active DNA demethylation, and cancer
… has the capacity to alter chromatin structure directly through its … that 5-hmC is enriched at:
(1) promoters that have low CpG … gene regulation through associations with various interacting …
(1) promoters that have low CpG … gene regulation through associations with various interacting …
Making it or breaking it: DNA methylation and genome integrity
… CpG sites, which are adjacent to an A/T-rich sequence [29]. … CTCF may also influence the
three-dimensional organization … how alterations in DNA methylation and demethylation perturb …
three-dimensional organization … how alterations in DNA methylation and demethylation perturb …