Methylation-eQTL analysis in cancer research
… studying associations of methylation and expression … methylation sites do not occur exclusively
in CpG islands or gene promoters, and the effect of DNA methylation on gene expression …
in CpG islands or gene promoters, and the effect of DNA methylation on gene expression …
High EREG expression is predictive of better outcomes in rectal cancer patients receiving neoadjuvant concurrent chemoradiotherapy
CY Lin, PL Hsieh, CL Chou, CC Yang, SW Lee… - Oncology, 2020 - karger.com
… examine the association between EREG expression and CCRT … The CpG island methylator
phenotype subtype of colon cancer is … methylation as a surrogate for CpG island methylator …
phenotype subtype of colon cancer is … methylation as a surrogate for CpG island methylator …
Epidemiology and molecular-pathologic characteristics of CpG Island methylator phenotype (CIMP) in colorectal cancer
… We assessed the associations of these characteristics in a … in the regulation of gene expression
and are organized at … be associated with CpG island methylation in bronchial epithelium …
and are organized at … be associated with CpG island methylation in bronchial epithelium …
Effect of DNA methylation status on first-line anti-epidermal growth factor receptor treatment in patients with metastatic colorectal cancer
H Osumi, K Ouchi, E Shinozaki, S Takahashi… - International Journal of …, 2022 - Springer
… The concept of CpG island methylator phenotype (CIMP) was … the association between the
genome-wide DNA methylation … The expression of EREG and AREG have a strong inverse …
genome-wide DNA methylation … The expression of EREG and AREG have a strong inverse …
[HTML][HTML] Global gene methylation profiling of common warts caused by human papillomaviruses infection
MA Alghamdi, LN Al-Eitan, AH Tarkhan… - Saudi Journal of …, 2021 - Elsevier
… focused on the methylation status of CpG islands, CpG sites, … The expression and methylation
levels of these genes in HPV… reported to have relevant associations with disease. The …
levels of these genes in HPV… reported to have relevant associations with disease. The …
The role of EREG/EGFR pathway in tumor progression
WL Cheng, PH Feng, KY Lee, KY Chen… - International journal of …, 2021 - mdpi.com
… expression was markedly limited by DNA methylation, which is associated with CpG island
methylator phenotype … Both AREG and EREG gene expression are negatively regulated by …
methylator phenotype … Both AREG and EREG gene expression are negatively regulated by …
Amphiregulin Expression Is a Predictive Biomarker for EGFR Inhibition in Metastatic Colorectal Cancer: Combined Analysis of Three Randomized Trials
A Stahler, S Stintzing, DP Modest, I Ricard… - Clinical Cancer …, 2020 - AACR
… expression was detected in 343 (>median) and 172 (>3rd quartile) patients. High AREG
expression … 51.6%, P = 0.004) compared to low expression at both threshold values. This effect …
expression … 51.6%, P = 0.004) compared to low expression at both threshold values. This effect …
Epigenome-wide methylation analysis of colorectal carcinoma, adenoma and normal tissue reveals novel biomarkers addressing unmet clinical needs
… with MSI status and CpG island methylator phenotype (CIMP). A … methylation and subsequent
low EREG gene expression … methylation was identified as one of the top 14 methylation …
low EREG gene expression … methylation was identified as one of the top 14 methylation …
Genome-wide DNA methylation status is a predictor of the efficacy of anti-EGFR antibodies in the second-line treatment of metastatic colorectal cancer: Translational …
K Ouchi, S Takahashi, K Sasaki, Y Yoshida… - International Journal of …, 2024 - Springer
… DNA methylation, such as the CpG island methylator phenotype (CIMP… of gene expression
[30]. Otsuki et al. reported that the … the association between aberrant DNA methylation and the …
[30]. Otsuki et al. reported that the … the association between aberrant DNA methylation and the …
[HTML][HTML] Synchronous and metachronous colorectal liver metastases: impact of primary tumor location on patterns of recurrence and survival after hepatic resection
I Garajova, R Balsano, C Tommasi… - Acta Bio Medica …, 2021 - ncbi.nlm.nih.gov
… to determine the joint association of several clinical factors … , CpG island methylation and
ERCC1 expression in RCC (19… microsatellite instability, high CpG island methylation (CIMP), …
ERCC1 expression in RCC (19… microsatellite instability, high CpG island methylation (CIMP), …