Polymorphism of interleukin-1β and interleukin-1 receptor antagonist genes in children with autism spectrum disorders
K Saad, AEM Abdallah, AA Abdel-Rahman… - Progress in Neuro …, 2020 - Elsevier
… interleukin-1 beta (IL-1β) and IL-1 receptor antagonist (IL-… Egyptian children with autism
spectrum disorder (ASD) and in … IL-1β gene promoter and IL1RA and assessed the association …
spectrum disorder (ASD) and in … IL-1β gene promoter and IL1RA and assessed the association …
Therapeutic role of interleukin-1 receptor antagonist in pancreatic diseases: mendelian randomization study
S Yuan, Y Miao, X Ruan, J Chen, X Li… - Frontiers in …, 2023 - frontiersin.org
… This MR study validated the genetic instrument for IL-1RA by examining the associations
of … Using this genetic instrument, we found consistent associations of genetically predicted …
of … Using this genetic instrument, we found consistent associations of genetically predicted …
The interactions between interleukin-1 family genes: IL1A, IL1B, IL1RN, and obesity parameters
E Maculewicz, B Antkowiak, O Antkowiak, A Borecka… - BMC genomics, 2022 - Springer
… Taking into account the role of IL-1 cytokines and receptors in … variations and associations
among IL-1 family genes may be … genetic polymorphisms and interrelationships among genes …
among IL-1 family genes may be … genetic polymorphisms and interrelationships among genes …
Interleukin 1 receptor antagonist (IL1RN) gene variants predict radiographic severity of knee osteoarthritis and risk of incident disease
…, M Hochberg, JM Jordan, B Mitchell… - … Rheumatic Diseases, 2020 - ard.bmj.com
… asked whether the association of the TTG haplotype with more severe disease was limited to
OA, … plasma IL-6 and hsCRP in association with increased clinical disease activity (DAS28). …
OA, … plasma IL-6 and hsCRP in association with increased clinical disease activity (DAS28). …
Mendelian randomization study for the roles of IL-18 and IL-1 receptor antagonist in the development of inflammatory bowel disease
J Mi, Z Liu, S Pei, X Wu, N Zhao, L Jiang… - International …, 2022 - Elsevier
… causal associations of IL-18 and IL-1Ra (receptor antagonist) … Given that anakinra, an
interleukin-1 receptor antagonist, … diseases, our results provided evidence for IL-1R antagonist …
interleukin-1 receptor antagonist, … diseases, our results provided evidence for IL-1R antagonist …
The revisited role of interleukin-1 alpha and beta in autoimmune and inflammatory disorders and in comorbidities
… prototypical inflammatory cytokine (IL-1) in human diseases. IL-1α and IL-1β deregulated
signaling causes devastating diseases manifested by severe acute or chronic inflammation. …
signaling causes devastating diseases manifested by severe acute or chronic inflammation. …
Serum interleukin-6, interleukin-8, and interleukin-1 receptor antagonist levels in South Indian fibromyalgia patients and its correlation with disease severity
S Surendran, CB Mithun, VS Chandran… - Indian Journal of …, 2021 - journals.lww.com
… patterns of interleukin-1 receptor antagonist (IL-1Ra), interleukin-8 (IL-8), and interleukin-6
(IL-6) in Indian females with fibromyalgia and its correlation with the disease severity. …
(IL-6) in Indian females with fibromyalgia and its correlation with the disease severity. …
Interleukin-1 and the inflammasome as therapeutic targets in cardiovascular disease
… Indeed, proinflammatory stimuli, such as oxidized lipoproteins, stimulate IL-1 gene expression
and further enhance disease progression in an autostimulatory cycle. IL-1β also has a …
and further enhance disease progression in an autostimulatory cycle. IL-1β also has a …
IL (Interleukin)-1 receptor antagonist increases ang (angiotensin [1–7]) and decreases blood pressure in obese individuals
IL (Interleukin)-1 antagonism decreases blood pressure in obese individuals. The underlying
mechanisms are unknown. Based on experimental data, we hypothesized an effect of IL-1 …
mechanisms are unknown. Based on experimental data, we hypothesized an effect of IL-1 …
Autoantibodies against interleukin-1 receptor antagonist in multisystem inflammatory syndrome in children: a multicentre, retrospective, cohort study
J Pfeifer, B Thurner, C Kessel, N Fadle… - The Lancet …, 2022 - thelancet.com
… Recently, neutralising autoantibodies against inflammatory receptor antagonists progranulin
and interleukin-1 receptor antagonist (IL-1Ra) were found in adult patients with critical …
and interleukin-1 receptor antagonist (IL-1Ra) were found in adult patients with critical …