Epidemiology of atypical hemolytic uremic syndrome: a systematic literature review

K Yan, K Desai, L Gullapalli, E Druyts… - Clinical …, 2020 - Taylor & Francis
… The population of interest were individuals diagnosed with atypical hemolytic uremic syndrome.
Studies focusing exclusively on pregnancy-associated aHUS (p-aHUS) were excluded. …

How I diagnose and treat atypical hemolytic uremic syndrome

F Fakhouri, N Schwotzer… - Blood, The Journal of …, 2023 - ashpublications.org
… Our understanding and management of atypical hemolytic uremic syndrome (aHUS) have
dramatically improved in the last decade. aHUS has been established as a prototypic disease …

Typical and atypical hemolytic uremic syndrome in the critically ill

CL Manrique-Caballero… - Critical Care …, 2020 - criticalcare.theclinics.com
… Shiga toxin-associated hemolytic uremic syndrome and atypical hemolytic uremic
syndrome constitute the most common presentations in children and adults respectively. …

Atypical hemolytic uremic syndrome: new challenges in the complement blockage era

AI Avila Bernabeu, T Cavero Escribano, M Cao Vilarino - Nephron, 2020 - karger.com
Atypical hemolytic uremic syndrome (aHUS) is a rare cause of thrombotic microangiopathy
(TMA), characterized by microangiopathic hemolytic anemia, consumptive thrombocytopenia, …

Clinical characteristics and outcome of canadian patients diagnosed with atypical hemolytic uremic syndrome

AL Lapeyraque, M Bitzan, I Al-Dakkak… - … Journal of Kidney …, 2020 - journals.sagepub.com
Background: Atypical hemolytic uremic syndrome (aHUS) is an extremely rare, heterogeneous
disease of uncontrolled activation of the alternative complement pathway that is difficult to …

Familial risk of developing atypical hemolytic-uremic syndrome

E Arjona, A Huerta… - Blood, The Journal …, 2020 - ashpublications.org
Atypical hemolytic-uremic syndrome (aHUS) is a life-threatening disease that in most cases
progresses to end-stage kidney disease. 1 Rare pathogenic mutations in complement …

Systematic review of atypical hemolytic uremic syndrome biomarkers

R Raina, SK Sethi, MA Dragon-Durey, A Khooblall… - Pediatric …, 2022 - Springer
… of atypical hemolytic uremic syndrome. We have conducted a systematic review on the
aHUS biomarkers: C3, C5a, C5b-9, factor B, complement factor B, H, and I, CH50, AH50, d-dimer, …

[HTML][HTML] Genetic atypical hemolytic-uremic syndrome

M Noris, E Bresin, C Mele, G Remuzzi - 2021 - europepmc.org
Hemolytic-uremic syndrome (HUS) is characterized by hemolytic anemia, thrombocytopenia,
and renal failure caused by platelet thrombi in the microcirculation of the kidney and other …

[HTML][HTML] Consensus regarding diagnosis and management of atypical hemolytic uremic syndrome

H Lee, E Kang, HG Kang, YH Kim, JS Kim… - The Korean Journal …, 2020 - ncbi.nlm.nih.gov
… , despite recent advances in understanding the mechanisms of several types of TMA syndrome.
Atypical hemolytic uremic syndrome (aHUS) is caused by a genetic or acquired defect in …

Eculizumab discontinuation in children and adults with atypical hemolytic-uremic syndrome: a prospective multicenter study

F Fakhouri, M Fila, A Hummel, D Ribes… - Blood, The Journal …, 2021 - ashpublications.org
… The optimal duration of eculizumab treatment in patients with atypical hemolytic uremic
syndrome (aHUS) remains poorly defined. We conducted a prospective national multicenter open…