[HTML][HTML] Higher levels of anti-phosphorylcholine autoantibodies in early rheumatoid arthritis indicate lower risk of incident cardiovascular events

S Ajeganova, MLE Andersson, J Frostegård… - Arthritis Research & …, 2021 - Springer
… We hypothesized that the association between IgM anti-PC and the risk of CV outcome is
different in the presence of CV risk factors. We therefore further performed analyses within the …

Antibodies against phosphorylcholine and protection against atherosclerosis, cardiovascular disease and chronic inflammation

J Frostegård - Expert Review of Clinical Immunology, 2022 - Taylor & Francis
… could be related to the complexity of the LDL-oxidation process where antigens exposed
could vary to some extent, and there may also be differences in methods used for antibody

Immunoglobulin A antibodies against phosphorylcholine in rheumatoid arthritis patients and its association with clinical outcomes

A Syed - 2021 - diva-portal.org
… with the clinical outcomes. Potential immunomodulatory … antibody to target the root
causes of the inflammation and treat patients with early RA, thereby atherosclerosis and CVD

Different subclasses and isotypes of antibodies against phosphorylcholine in haemodialysis patients: association with mortality

SK Samal, AR Qureshi, M Rahman… - Clinical & …, 2020 - academic.oup.com
… We also divided patients into inflamed C-reactive protein (CRP) > 5·6 mg/ml and non-inflamed
CRP. Antibody levels were determined by in-house enzyme-linked immunosorbent assay. …

[HTML][HTML] Antibodies against Phosphorylcholine—Implications for Chronic Inflammatory Diseases

J Frostegård - Metabolites, 2023 - mdpi.com
Atherosclerosis and its main consequence, cardiovascular disease (CVD) are nowadays
regarded as chronic inflammatory disease conditions, and CVD is the main cause of death in …

[HTML][HTML] IgM antibodies against malondialdehyde and phosphorylcholine in different systemic rheumatic diseases

D Thiagarajan, N Oparina, S Lundström, R Zubarev… - Scientific reports, 2020 - nature.com
… The antibody levels were used for cases vs controls and cross-disease analysis. Statistical …
for each antibody. The correlation between antibody level and cardiovascular score (CV) was …

[PDF][PDF] Immunoglobulin G1 antibodies against phosphorylcholine are associated with protection in systemic lupus erythematosus and atherosclerosis: Potential …

D Thiagarajan, R Fiskesund, A Frostegård… - ACR open …, 2020 - Wiley Online Library
phosphocholine (POVPC); the antibody binding is tested for all known antigens that expose
PC. Capsular polysaccharide (C-PS), POVPC conjugated with bovine serum albumin (BSA), …

Phosphorylcholine antibodies restrict infarct size and left ventricular remodelling by attenuating the unreperfused post‐ischaemic inflammatory response

NJ Pluijmert, RCM de Jong, MR de Vries… - Journal of Cellular …, 2021 - Wiley Online Library
… mice that a specific clone of IgM autoantibodies against phosphorylcholine, termed E06 or
T15 … IgM phosphorylcholine antibodies are associated with an increased risk of cardiovascular

Antibodies against phosphorylcholine and malondialdehyde during the first two years of life

D Thiagarajan, SL Lundström, G Pershagen… - The Journal of …, 2020 - journals.aai.org
… Abs against phosphorylcholine (anti-PC) and Abs against malondialdehyde (anti-MDA) may
be protective in chronic inflammation, like atherosclerosis and cardiovascular disease. It is …

Anti-phospholipid autoantibodies in human diseases

R Qin, H Wu, H Guan, C Tang, Z Zheng, C Deng… - Clinical …, 2023 - Elsevier
… anti-phospholipid autoantibody levels in patients with antiphospholipid syndrome, …
cardiovascular diseases. However, the underlying mechanisms of anti-phospholipid autoantibodies