Leveraging and manufacturing in vitro multicellular spheroid-based tumor cell model as a preclinical tool for translating dysregulated tumor metabolism into clinical …
T Wang, L Wang, G Wang, Y Zhuang - Bioresources and Bioprocessing, 2020 - Springer
… oncogenesis, tumor progression and invasion, pharmacokinetics… In human brain tumors, the
contribution of acetate oxidation to … Since the 1970s, organ and 3D cell culture models have …
contribution of acetate oxidation to … Since the 1970s, organ and 3D cell culture models have …
Three-dimensional culture system of cancer cells combined with biomaterials for drug screening
T Nii, K Makino, Y Tabata - Cancers, 2020 - mdpi.com
… This review introduces the in vitro research of 3D cell culture … tool to evaluate the cancer
invasion ability or perform a drug … to investigate the behavior of brain cancer cells embedded into …
invasion ability or perform a drug … to investigate the behavior of brain cancer cells embedded into …
Patient‐Derived Organoids as Therapy Screening Platforms in Cancer Patients
D Khorsandi, JW Yang, S Foster… - Advanced …, 2024 - Wiley Online Library
… The brain tumor PDOs (neurospheres) were evaluated for … U-251 MG cell spheroids. The
study further expanded its … 1), a platform of PDO-autologous T cell co-cultures was used for drug …
study further expanded its … 1), a platform of PDO-autologous T cell co-cultures was used for drug …
[PDF][PDF] Modeling the interaction between the microenvironment and tumor cells in brain tumors
C Pasqualini, T Kozaki, M Bruschi, THH Nguyen… - Neuron, 2020 - cell.com
… of tumor cell niche, angiogenesis, and invasion in brain tumors… over time, 3D cultures of brain
cancer cells as neurospheres … spheroids/organoids derived directly from fresh patient tumor …
cancer cells as neurospheres … spheroids/organoids derived directly from fresh patient tumor …
Human organ‐specific 3D cancer models produced by the stromal self‐assembly method of tissue engineering for the study of solid tumors
V Roy, B Magne, M Vaillancourt-Audet… - BioMed Research …, 2020 - Wiley Online Library
… In this review, we provide an overview of 3D cell culture models … It causes brain tumors, as
well as disfiguring skin lesions … to blood typing and autologous grafting, respectively. The 3D …
well as disfiguring skin lesions … to blood typing and autologous grafting, respectively. The 3D …
[PDF][PDF] Evaluation of comprehensive gene expression and NK cell-mediated killing in glioblastoma cell line-derived spheroids. Cancers 2021; 13 (19)
T Morimoto, T Nakazawa, R Matsuda, F Nishimura… - 2021 - researchgate.net
… ) is the most aggressive primary malignant brain tumor in adults. … NK cells expanded from
our specific culture conditions on a … supplemented with 5% autologous plasma and 3000 IU/mL …
our specific culture conditions on a … supplemented with 5% autologous plasma and 3000 IU/mL …
Historical evolution of spheroids and organoids, and possibilities of use in life sciences and medicine
ME Sakalem, MT De Sibio, FAS da Costa… - Biotechnology …, 2021 - Wiley Online Library
… of the most common 3D cell culture models available, as well as … corneal surfaces with
autologous cultivated corneal epithe… of stroma-mediated cancer cell invasion, matrix remodeling, …
autologous cultivated corneal epithe… of stroma-mediated cancer cell invasion, matrix remodeling, …
Innovative 3D model for the establishment of primary paediatric brain tumour cultures: new platform for the preclinical study of immunotherapeutic approaches
T Belardinilli - 2020 - iris.uniroma1.it
… lytic potential towards autologous primary renal cancer cells, … 3D cell cultures a comparison
of different types of cancer cell … study cancer cells in a context that recapitulates invasion and …
of different types of cancer cell … study cancer cells in a context that recapitulates invasion and …
Strategies to capitalize on cell spheroid therapeutic potential for tissue repair and disease modeling
KH Griffin, SW Fok, J Kent Leach - npj Regenerative Medicine, 2022 - nature.com
… spheroid use include limited donor supply for autologous models and the extensive time
required for spheroid … cells are still in monolayer culture before spheroid formation. Cells can be …
required for spheroid … cells are still in monolayer culture before spheroid formation. Cells can be …
Glioblastoma Vasculature: From its Critical Role in Tumor Survival to Relevant in Vitro Modelling
… , aggressive and lethal primary brain tumor in adults. According … reported GBM spheroids
comprise only one human or one … of stromal cells, and even autologous stromal cells, might be …
comprise only one human or one … of stromal cells, and even autologous stromal cells, might be …