Humoral immunity in atherosclerosis and myocardial infarction: from B cells to antibodies
… Associations of specific antibody levels and defined B-cell subsets … B cells and humoral
immunity in atherosclerotic cardiovascular disease. These include all aspects of B-cell immunity, …
immunity in atherosclerotic cardiovascular disease. These include all aspects of B-cell immunity, …
Immunity in atherosclerosis: focusing on T and B cells
AV Poznyak, EE Bezsonov, TV Popkova… - International Journal of …, 2021 - mdpi.com
… secrete poorly specific natural IgM antibodies, creating a rapid and T-cell-independent
humoral response. Secreted B1 antibodies are polyreactive and are the main defense against …
humoral response. Secreted B1 antibodies are polyreactive and are the main defense against …
Functional role of B cells in atherosclerosis
SD Ma, M Mussbacher, EV Galkina - Cells, 2021 - mdpi.com
… atherosclerosis-prone conditions. By summarizing current knowledge of B cells in and beyond
atherosclerosis… While OSE-derived antigens induce humoral response in atherosclerosis, …
atherosclerosis… While OSE-derived antigens induce humoral response in atherosclerosis, …
Role of the adaptive immune system in atherosclerosis
K Ley - Biochemical Society Transactions, 2020 - portlandpress.com
… , IgG antibodies with more atherosclerosis. Thus, both T and B cells play critical roles in
atherosclerosis. Modifying the adaptive immune response to ApoB holds promise for preventing …
atherosclerosis. Modifying the adaptive immune response to ApoB holds promise for preventing …
B cells in atherosclerosis: mechanisms and potential clinical applications
T Pattarabanjird, C Li, C McNamara - Basic to Translational Science, 2021 - jacc.org
… B cell–derived Igs modulate atherosclerosis, with a focus on the implications for potential
B-cell–targeted therapies for atherosclerotic … to induce a humoral response to limit the impact of …
B-cell–targeted therapies for atherosclerotic … to induce a humoral response to limit the impact of …
Beyond macrophages and T cells: B cells and immunoglobulins determine the fate of the atherosclerotic plaque
H Mangge, F Prüller, W Schnedl, W Renner… - International Journal of …, 2020 - mdpi.com
… fight against atherosclerotic endpoints. This review will reflect the putative role of B cells in
… We will also discuss the clinical therapeutic potency of B cell modulations on the process of …
… We will also discuss the clinical therapeutic potency of B cell modulations on the process of …
Gut microbiota and atherosclerosis: role of B cell for atherosclerosis focusing on the gut-immune-B2 cell axis
L Chen, T Ishigami, H Doi, K Arakawa… - Journal of Molecular …, 2020 - Springer
… Furthermore, a potential translational extension of the current research would be to better
characterize the specific humoral immunity in individuals with atherosclerosis. We sought to …
characterize the specific humoral immunity in individuals with atherosclerosis. We sought to …
B cell and CD4 T cell interactions promote development of atherosclerosis
C Tay, P Kanellakis, H Hosseini, A Cao… - … in immunology, 2020 - frontiersin.org
… differentiation and production of high affinity immunoglobulins that play a critical role in
humoral response, we next assessed the effect of genetic deletion of immunoglobulin μ-heavy …
humoral response, we next assessed the effect of genetic deletion of immunoglobulin μ-heavy …
Alarmin-activated B cells accelerate murine atherosclerosis after myocardial infarction via plasma cell-immunoglobulin-dependent mechanisms
T Kyaw, P Loveland, P Kanellakis, A Cao… - European heart …, 2021 - academic.oup.com
… atherosclerosis after MI and specifically identify key roles for alarmins in activating B cells
during MI; we also demonstrate that activated B cells … of established atherosclerosis to plaques …
during MI; we also demonstrate that activated B cells … of established atherosclerosis to plaques …
2019 Russell Ross Memorial Lecture in Vascular Biology: B Lymphocyte–Mediated Protective Immunity in Atherosclerosis
A Upadhye, JM Sturek… - Arteriosclerosis, thrombosis …, 2020 - Am Heart Assoc
… One of these areas with clear direct connections to therapeutic intervention is that of
protective humoral immunity mediated by B-1 lymphocytes. Recent work has unveiled surprising …
protective humoral immunity mediated by B-1 lymphocytes. Recent work has unveiled surprising …