BK polyomavirus-specific T cells as a diagnostic and prognostic marker for BK polyomavirus infections after pediatric kidney transplantation

T Ahlenstiel-Grunow, M Sester, U Sester… - …, 2020 - journals.lww.com
cellular immune response of a pediatric cohort with BKPyV-DNAemia after kidney
transplantation… In our study group, BKPyV-specific CD8 T cells were at least temporarily detected

Immunosuppression, BK polyomavirus infections, and BK polyomavirus-specific T cells after pediatric kidney transplantation

T Ahlenstiel-Grunow, L Pape - Pediatric Nephrology, 2020 - Springer
… replication and cellular immune response, … T cells were measured by cytokine flow cytometry,
as described before [40]. The diagnosis of BKPyVAN was based on standardized kidney

Diagnostics, treatment, and immune response in BK polyomavirus infection after pediatric kidney transplantation

T Ahlenstiel-Grunow, L Pape - Pediatric Nephrology, 2020 - Springer
immune response to BKPyV are described and their usability is discussed. There is growing
evidence that BKPyV-specific T cells … of diagnosis was 4 months after kidney transplantation […

A 2-fold Approach to Polyoma Virus (BK) Nephropathy in Kidney Transplants: Distinguishing Direct Virus Effects From Cognate T Cell–mediated Inflammation

…, D Kumar, O Viklicky, A Perkowska-Ptasinska… - …, 2021 - journals.lww.com
… but are an adaptive immune response facilitated by … T cell–mediated inflammation diagnosed
by the TCMR classifier, 15 , 16 , 26 mindful that positive scores may reflect T-cell responses

The effect of the BK polyomavirus large T antigen on the function and maturity of the CD4+ T cell subsets in kidney transplant recipients

…, A Afshari, J Roozbeh, SM Miresmaeili, A Javid - Transplant …, 2023 - Elsevier
… be efficient in treating and diagnosing BKPyV infections in kidney recipients. … T cells with
low expression of STAT-3 have an effective role in immune responses in renal transplantation […

[HTML][HTML] Innate immunity response to BK virus infection in polyomavirus-associated nephropathy in kidney transplant recipients

W Chancharoenthana, A Leelahavanichkul - Transplantology, 2022 - mdpi.com
polyomavirus-specific DNA … immune system is the differentiation of lymphoid B and T cell
lineages [67]. Notch functions also enhance regulatory T (Treg) cell function, activate the T cell

[HTML][HTML] … and meta-analysis of enzyme-linked immunosorbent spot (ELISPOT) assay for BK polyomavirus immune response monitoring after kidney transplantation

S Udomkarnjananun, SJ Kerr, MI Francke… - Journal of Clinical …, 2021 - Elsevier
… -γ as the cytokine for the T lymphocyte-specific immune response against BK viral antigens.
… the time that BK viruria or viremia is first detected. By this method one will be able to classify …

The natural history of BK polyomavirus and the host immune response after stem cell transplantation

…, K Lake, A Duell, B Litts, AE Seif, T Olson… - Clinical Infectious …, 2020 - academic.oup.com
patients, BKPyV replication is detected by nucleic … immunity. We hypothesized that BKPyV
was associated with decreased kidney function and that the measurement of BKPyV T cells

[HTML][HTML] Cellular immunity in BK polyomavirus associated nephropathy following adult kidney transplantation

…, U Grunwald, DL Dräger, T Neumann… - Transplantation …, 2022 - Elsevier
immune responses, especially cellular immune responses, is … -specific T cell levels may
help to distinguish patients with … BK polyomavirus-specific cellular immune responses are age…

[HTML][HTML] Allogeneic CD4 T Cells Sustain Effective BK Polyomavirus-Specific CD8 T Cell Response in Kidney Transplant Recipients

…, F Herr, JL Taupin, Y Taoufik, A Durrbach - Kidney International …, 2024 - Elsevier
… to restore BKPyV-specific immune responses. However, this approach entails a risk of
allogeneic … However, at the time of BKPyVAN diagnosis, CD4 and CD8 T cell counts were similar …