… been implicated in human primary ovarian insufficiency (POI) … in bmp15 mutant was due to
the reduced expression of … increased production and activity of activin from inhbaa in bmp15-/-;…

… caused by a heterozygous mutation in BMP15, accompanied by … by directly suppressing the
mRNA expression of FSH receptors in … Loss of BMP15 activity can result in defective follicle …

… -related fertility decline and premature ovarian insufficiency. … PBS, and endogenous peroxidase
activity was denatured with 3… ovarian expressions of BMP15, GDF9, and C-KIT decrease …

… expression and related protein abnormalities were structured to establish the role of etiological
genes associated … R68W is a deleterious mutation in POF patients, where BMP15 activity …

… amenorrhea due to premature ovarian failure and a pituitary … of mutant GDF-9/normal BMP15,
or even failure to form … and complexes and/or increased activity, whereby indicating that, …

… The Italian POI patients’ DNA were processed by targeted WES including 542 RefSeq genes
expressed or functioning during distinct reproductive or ovarian processes (eg DNA repair, …

… Most of the genes related to POI in mice have shown a … lead to reduction in the expression
of apoptosis-related proteins, … causative genes and influences a variety of biological activities, …

… mutations of BMP15 cause primary ovarian insufficiency (POI… levels of the proteins might
reduce granulosa cell mitosis and … an effect since the BMP15 gene is expressed exclusively in …

… BMP15 gene and its missense variants have been identified as a potential candidate for
premature ovarian insufficiency (… mutations associated with primary ovarian insufficiency. Hum …

… expression patterns of bmp15 without much exploration of the biological activities and …
lack of vitellogenesis in bmp15 mutant was due to the reduced expression of cyp19a1a, we …