… clarified the pathogenesis, at the molecular level, of thyroid carcinomas and … BRAF
V600E-mutated PTC [26] (Table 1). The association of BRAF mutation and PTC at advanced clinical …

… Mutated BRAF PTC has been related to different clinical-… pathways implicated in the
pathogenetic process of aggressive TC. … BRAF mutation in papillary thyroid carcinoma: predictive …

… of papillary thyroid carcinoma (FVPTC) has an indolent clinical … by the absence of the BRAF
V600E mutation [17], whereas ~30… Pathogenic variants were defined as known pathogenic …

… The extent to which routine genomic sequencing can identify relevant secondary genomic
alterations among BRAF V600E -mutant papillary thyroid carcinoma (PTC) is unknown. Such …

… discusses the molecular mechanisms associated to the pathogenesis of different types of TC
and their clinical relevance. … BRAF mutations are associated with some histological types of …

… , such as RET rearrangements and BRAF V600E as it calls into question their role of driver
genes. ITH is also predicted to play a major clinical role as it could have a significant impact …

… papillary thyroid carcinoma (PTC) have specific genetic alterations that correlate with
morphological classifications: RAS-like tumors (RLTs) and BRAF … with DICER1 pathogenic …

… BRAF and RAS mutational status, patient gender, clinical stage, histological variation, and
other categorical data were given as frequencies and percentages. Age and tumor size were …

… It is frequently activated in thyroid cancer through BRAF mutation, RAS mutation, and RET/…
) BRAF mutation in papillary thyroid cancer: pathogenic role, molecular bases, and clinical …

… of fusions in this papillary thyroid cancer subgroup suggested a correlation of gene fusions
with the phenotype that does not belong to the BRAF V600E-mutant or RAS-mutant group. …